阿司匹林作为关节置换术后静脉血栓栓塞预防的循证医学证据。
Evidence-base for aspirin as venous thromboembolic prophylaxis following joint replacement.
机构信息
South Tees Hospitals NHS Foundation Trust, Marton Road, Middlesbrough TS4 3BW, UK.
Newcastle Hospitals NHS Foundation Trust, Freeman Road, High Heaton, Newcastle upon Tyne, NE7 7DN, UK.
出版信息
Bone Joint Res. 2014 May;3(5):146-9. doi: 10.1302/2046-3758.35.2000225.
Abstract
The National Institute for Health and Clinical Excellence (NICE) has thus far relied on historical data and predominantly industry-sponsored trials to provide evidence for venous thromboembolic (VTE) prophylaxis in joint replacement patients. We argue that the NICE guidelines may be reliant on assumptions that are in need of revision. Following the publication of large scale, independent observational studies showing little difference between low-molecular-weight heparins and aspirin, and recent changes to the guidance provided by other international bodies, should NICE reconsider their recommendations? Cite this article: Bone Joint Res 2014;3:146-9.
摘要
国家卫生与临床优化研究所（NICE）迄今为止一直依赖历史数据和主要由行业赞助的试验来为关节置换患者的静脉血栓栓塞（VTE）预防提供证据。我们认为，NICE 指南可能依赖于需要修订的假设。在发表了大型独立观察性研究表明低分子肝素和阿司匹林之间几乎没有差异之后，以及其他国际机构的指导意见最近发生变化之后，NICE 是否应该重新考虑他们的建议？引用本文：Bone Joint Res 2014;3:146-9.
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