Muñoz González A, Cuello J P, Rodríguez Cruz P M, Iglesias Mohedano A M, Domínguez Rubio R, Romero Delgado F, García Pastor A, Guzmán de Villoria Lebiedziejswki J, Fernández García P, Romero Martínez J, Ezpeleta Echevarri D, Díaz Otero F, Vázquez Alen P, Villanueva Osorio J A, Gil Núñez A
Servicio de Neurología, Hospital General Universitario Gregorio Marañón, Madrid, España.
Servicio de Neurología, Hospital General Universitario Gregorio Marañón, Madrid, España.
Neurologia. 2015 Sep;30(7):393-400. doi: 10.1016/j.nrl.2014.03.007. Epub 2014 May 17.
Spontaneous spinal epidural haematoma (SSEH) has an estimated incidence of one per million inhabitants. It is classified as spontaneous when no identifiable cause can be linked to its onset.
To describe a sample of patients with SSEH and analyse variables related to its functional prognosis.
Retrospective study carried out in patients diagnosed with SSEH between 2001 and 2013 in our hospital.
We included 13 subjects (7 men) with a mean age of 71 years. Of the total, 62% had hypertension and 54% were treated with oral anticoagulants; of the latter, 57% had an International Normalised Ratio above 3. The most frequent manifestation was spinal column pain (85%). Nearly all subjects presented an associated neurological deficit, whether sensory-motor (70%), pure motor (15%), or pure sensory (7%). Five patients underwent surgical treatment and 8 had conservative treatment. After one year, 3 of the patients treated surgically and 4 of those on conservative treatment had a score of 2 or lower on the modified Rankin Scale. Poorer prognosis was observed in patients with anticoagulant therapy, large haematomas, location in the lumbar region, and more pronounced motor disability at onset.
Old age, hypertension, and anticoagulant therapy are the main risk factors for SSEH. The typical presentation consists of back pain with subsequent motor deficit. In patients with established motor symptoms, surgical treatment within the first 24hours seems to be the best option.
自发性脊髓硬膜外血肿(SSEH)的估计发病率为每百万居民中有一例。当无法确定其发病的可识别原因时,它被归类为自发性。
描述一组SSEH患者样本,并分析与其功能预后相关的变量。
对2001年至2013年在我院诊断为SSEH的患者进行回顾性研究。
我们纳入了13名受试者(7名男性),平均年龄为71岁。其中,62%患有高血压,54%接受口服抗凝剂治疗;在后者中,57%的国际标准化比值高于3。最常见的表现是脊柱疼痛(85%)。几乎所有受试者都出现了相关的神经功能缺损,无论是感觉运动型(70%)、单纯运动型(15%)还是单纯感觉型(7%)。5名患者接受了手术治疗,8名接受了保守治疗。一年后,接受手术治疗的患者中有3名,接受保守治疗的患者中有4名在改良Rankin量表上的得分≤2分。在接受抗凝治疗、血肿较大、位于腰椎区域以及发病时运动障碍更明显的患者中观察到预后较差。
老年、高血压和抗凝治疗是SSEH的主要危险因素。典型表现为背痛伴随后续运动功能缺损。对于已出现运动症状的患者,在最初24小时内进行手术治疗似乎是最佳选择。