Martínez Bermejo A, Pascual Castroviejo I, López Martín V, Arcas J, Pérez Higueras A
Neurologia. 1989 Oct;4(8):296-9.
We report four cases of acquired aphasia with epilepsy syndrome or Landau-Kleffner syndrome in three boys and one girl who were previously in good health. Along with the clinical picture, we describe cerebral arteriographic findings, which consisted of obstructive arteriopathy of small and medium size vessels in delimited areas. A specific cause of the arteriopathy was not found in any case. We discuss the treatment (corticosteroids and calcium antagonists) and the course of the patients. In front of the possibility of being isolated cases, we discuss the interest of performing cerebral angiographic studies in patients with Landau-Kleffner syndrome in initial stage in order to confirm the consistence of these findings and the adequate treatment.
我们报告了4例获得性失语伴癫痫综合征或Landau-Kleffner综合征的病例，其中3例为男孩，1例为女孩，他们之前身体健康。除临床表现外，我们还描述了脑动脉造影结果，表现为特定区域中小血管的阻塞性动脉病。所有病例均未发现动脉病的具体病因。我们讨论了治疗方法（皮质类固醇和钙拮抗剂）及患者的病程。鉴于可能是孤立病例，我们探讨了对处于疾病初期的Landau-Kleffner综合征患者进行脑血管造影研究的意义，以确认这些发现的一致性及合适的治疗方法。
