Özen Anıl, Unal Ertekin Utku, Mola Serkan, Erkengel Ibrahim, Kiris Erman, Aksöyek Aysen, Saritas Ahmet, Birincioğlu Cemal Levent
Türkiye Yüksek İhtisas Hospital, Cardiovascular Surgery Clinic, Ankara, Turkey.
Türkiye Yüksek İhtisas Hospital, Cardiovascular Surgery Clinic, Ankara, Turkey
Vascular. 2015 Apr;23(2):120-3. doi: 10.1177/1708538114533539. Epub 2014 May 19.
To assess the ability of Glasgow Aneurysm Score in predicting postoperative mortality for ruptured aortic aneurysm which may assist in decision making regarding the open surgical repair of an individual patient.
A total of 121 patients diagnosed of ruptured abdominal aortic aneurysm who underwent open surgery in our hospital between 1999 and 2013 were included. The Glasgow Aneurysm Score for each patient was graded according to the Glasgow Aneurysm Score (Glasgow Aneurysm Score = age in years + 17 for shock + 7 for myocardial disease + 10 for cerebrovascular disease + 14 for renal disease). The groups were divided as Group 1 (containing the patients who died) and Group 2 (the patients who were discharged). The Glasgow Aneurysm Scores amongst the groups were compared.
Out of 121 patients, 108 (89.3%) were males and 13 (10.7%) were females. The in-hospital mortality was 48 patients (39.7%). The Glasgow Aneurysm Score was 84.15 ± 15.94 in Group 1 and 75.14 ± 14.67 in Group 2 which revealed significance (p = 0.002). The most appropriate cut-off value for Glasgow Aneurysm Score was determined as 78.5 (AUC = 0.669, p = 0.002, sensitivity: 64.6%, specificity: 60.3%). Glasgow Aneurysm Score value above 78.5 is associated with almost threefold increase in mortality (p = 0.007, OR:2.76, 95% CI 1.30-5.89). In further logistic regression models, Glasgow Aneurysm Score value and preoperative hematocrit values were found to be independent predictors for mortality (p = 0.023 and p = 0.007, respectively).
Glasgow Aneurysm Score may have a predictive value for outcome of patients with ruptured abdominal aortic aneurysm undergoing open surgical procedure and it appears to be a useful tool in clinical decision-making of an individual patient when integrated with clinical experience.
评估格拉斯哥动脉瘤评分预测破裂性主动脉瘤术后死亡率的能力,这可能有助于对个体患者进行开放性手术修复的决策。
纳入1999年至2013年期间在我院接受开放性手术的121例诊断为破裂性腹主动脉瘤的患者。根据格拉斯哥动脉瘤评分(格拉斯哥动脉瘤评分=年龄(岁)+休克时加17+心肌病时加7+脑血管病时加10+肾病时加14)对每位患者进行格拉斯哥动脉瘤评分分级。将患者分为1组(包括死亡患者)和2组(出院患者)。比较两组之间的格拉斯哥动脉瘤评分。
121例患者中,男性108例(89.3%),女性13例(10.7%)。院内死亡率为48例(39.7%)。1组格拉斯哥动脉瘤评分为84.15±15.94,2组为75.14±14.67,差异有统计学意义(p=0.002)。格拉斯哥动脉瘤评分的最合适截断值确定为78.5(曲线下面积=0.669,p=0.002,敏感性:64.6%,特异性:60.3%)。格拉斯哥动脉瘤评分值高于78.5与死亡率几乎增加三倍相关(p=0.007,比值比:2.76,95%可信区间1.30-5.89)。在进一步的逻辑回归模型中,发现格拉斯哥动脉瘤评分值和术前血细胞比容值是死亡率的独立预测因素(分别为p=0.023和p=0.007)。
格拉斯哥动脉瘤评分可能对接受开放性手术的破裂性腹主动脉瘤患者的预后具有预测价值,并且在结合临床经验时,它似乎是个体患者临床决策中的一个有用工具。