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当前用于在痤疮治疗中有效递送生物活性药物分子的纳米技术方法。

Current nanotechnological approaches for an effective delivery of bio-active drug molecules in the treatment of acne.

作者信息

Garg Tarun

机构信息

a Department of Pharmaceutics , ISF College of Pharmacy , Moga, Punjab , India.

出版信息

Artif Cells Nanomed Biotechnol. 2016;44(1):98-105. doi: 10.3109/21691401.2014.916715. Epub 2014 May 20.

DOI:10.3109/21691401.2014.916715
PMID:24844191
Abstract

Acne is a chronic inflammatory human skin disease, characterized by areas of skin with seborrhoea, comedones, papules, nodules, pimples, and possibly scarring with lesions occurring on face, neck, and back. Nanotechnological approaches such as particulate (solid lipid nanoparticles and microspheres), vesicular (liposomes and niosomes), colloidal drug delivery systems (micro-emulsion and nano-emulsion), and miscellaneous systems (aerosol foams and micro-sponges) have an important place in acne therapy. These approaches have an enormous opportunity for the designing of a novel, low-dose and effective treatment systems to control acne disease. In this review, we specially focus on the different nanotechnological approaches for an effective treatment of acne.

摘要

痤疮是一种慢性炎症性人类皮肤病,其特征是皮肤出现皮脂溢、粉刺、丘疹、结节、脓疱,可能还有疤痕,病变发生在面部、颈部和背部。纳米技术方法,如颗粒剂(固体脂质纳米粒和微球)、囊泡剂(脂质体和非离子表面活性剂囊泡)、胶体给药系统(微乳和纳米乳)以及其他系统(气雾剂泡沫和微海绵)在痤疮治疗中占有重要地位。这些方法为设计新型、低剂量且有效的治疗系统以控制痤疮疾病提供了巨大机遇。在本综述中,我们特别关注用于有效治疗痤疮的不同纳米技术方法。

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Current nanotechnological approaches for an effective delivery of bio-active drug molecules in the treatment of acne.当前用于在痤疮治疗中有效递送生物活性药物分子的纳米技术方法。
Artif Cells Nanomed Biotechnol. 2016;44(1):98-105. doi: 10.3109/21691401.2014.916715. Epub 2014 May 20.
2
[Acne: pathogenesis and therapy].[痤疮:发病机制与治疗]
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[Therapeutic possibilities for acne vulgaris].[寻常痤疮的治疗可能性]
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Skin barrier and microbiome in acne.痤疮的皮肤屏障与微生物组。
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Novel pharmacological approaches for the treatment of acne vulgaris.治疗寻常痤疮的新型药理学方法。
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