Schramel P, Lill G, Hasse S, Klose B J
Gesellschaft für Strahlen- und Umweltforschung mbH, Institut für Okologische Chemie, Neuherberg, FRG.
Biol Trace Elem Res. 1988 Jun;16(1):67-75. doi: 10.1007/BF02795335.
The concentrations of the essential trace elements Cu, Fe, and Zn, and of the mineral elements Ca, K, Mg, and P during the perinatal period in human placenta and in the blood of the mother and the newborn (cord blood) were determined. Breast milk (colostrum and transitory milk) was also included to permit correlations between the different compartments. No correlations were found. The uptake by nutrition and the body-pools of the mother and their mobilization for these elements seem to be sufficiently high for an adequate supply of the fetus and the milk in the geographical region of Munich (Bavaria, FRG) under these investigations. Differences in the mineral-and trace element concentrations of colostrum and transitory milk for the elements P and Zn and to a lesser extent for Ca and Mg were observed. Additionally, breast milk samples from different geographical regions in Bavaria were investigated. Results for the heavy metals Cd, Hg, and Pb, and for the essential trace element Se are also presented for these samples, and can be seen as a reflection of the overall environmental and dietary influences during pregnancy in these geographical regions. ICP (Inductively Coupled Plasma)-emission spectrometry was used for the determination of the elements Cu, Fe, Zn, Ca, K, Mg, and P. For the additionally given elements in the milk-samples anodic stripping voltammetry (DPASV) (Cd, Pb), hydride atomic absorption spectrometry (AAS) (Se), and cold vapor AAS (Hg) were applied.
测定了人胎盘以及母亲和新生儿（脐带血）血液围产期必需微量元素铜、铁和锌以及矿物质元素钙、钾、镁和磷的浓度。还纳入了母乳（初乳和过渡乳），以便对不同部分之间进行关联分析。未发现相关性。在这些调查中，在慕尼黑（联邦德国巴伐利亚州）地区，母亲通过营养摄入这些元素及其体内储备，以及为满足胎儿和乳汁需求而进行的元素调动，似乎足以提供充足的供应。观察到初乳和过渡乳中磷和锌元素以及程度稍轻的钙和镁元素的矿物质和微量元素浓度存在差异。此外，还对巴伐利亚不同地理区域的母乳样本进行了调查。还给出了这些样本中重金属镉、汞和铅以及必需微量元素硒的结果，这些结果可被视为这些地理区域孕期总体环境和饮食影响的反映。采用电感耦合等离子体（ICP）发射光谱法测定铜、铁、锌、钙、钾、镁和磷元素。对于母乳样本中额外测定的元素，采用阳极溶出伏安法（DPASV）（镉、铅）、氢化物原子吸收光谱法（AAS）（硒）和冷蒸气AAS（汞）进行测定。
