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暴露于非法药物的致畸风险。

Teratogenic risks from exposure to illicit drugs.

机构信息

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of New Mexico School of Medicine, MSC10 5580, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of New Mexico School of Medicine, MSC10 5580, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA.

出版信息

Obstet Gynecol Clin North Am. 2014 Jun;41(2):229-39. doi: 10.1016/j.ogc.2014.02.008. Epub 2014 Mar 29.

DOI:10.1016/j.ogc.2014.02.008
PMID:24845487
Abstract

Substance use is prevalent in the United States, especially in the reproductive age population. Even though a reduction in substance use may occur during pregnancy, some women may not alter their drug use patterns until at least pregnancy is confirmed. For these reasons, a large number of fetuses are exposed to illicit substances, including during critical stages of organogenesis. Associating illicit drug use with eventual pregnancy outcome is difficult. This article presents issues pertaining to limitations with published investigations about fetal risks and describes the most current information in humans about fetal effects from specific illicit substances.

摘要

在美国,物质滥用很普遍,尤其是在生殖年龄段的人群中。尽管怀孕期间物质滥用可能会减少,但一些女性可能至少要等到怀孕得到确认后才会改变她们的药物使用模式。由于这些原因,大量胎儿接触到包括在器官发生的关键阶段的非法物质。将非法药物使用与最终的怀孕结果联系起来是困难的。本文介绍了与已发表的关于胎儿风险的调查研究的局限性相关的问题,并描述了关于特定非法物质对胎儿影响的最新人类信息。

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Teratogenic risks from exposure to illicit drugs.暴露于非法药物的致畸风险。
Obstet Gynecol Clin North Am. 2014 Jun;41(2):229-39. doi: 10.1016/j.ogc.2014.02.008. Epub 2014 Mar 29.
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Maternal and fetal effects from substance use.物质使用对母婴的影响。
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Smoke, alcohol consumption and illicit drug use in an Italian population of pregnant women.意大利孕妇人群中的吸烟、饮酒和非法药物使用情况。
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The effects of drug abuse on pregnancy.药物滥用对妊娠的影响。
Curr Opin Obstet Gynecol. 2007 Dec;19(6):578-85. doi: 10.1097/GCO.0b013e3282f1bf17.
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The consequences of maternal substance abuse for the child exposed in utero.孕期母亲药物滥用对胎儿的影响。
Psychosomatics. 1991 Summer;32(3):268-74. doi: 10.1016/S0033-3182(91)72064-1.
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Adverse consequences of prenatal illicit drug exposure.产前接触非法药物的不良后果。
Curr Opin Obstet Gynecol. 1996 Dec;8(6):403-11.
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Obstetric and neonatal effects of drugs of abuse.滥用药物对产科和新生儿的影响。
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