Roswall Nina, Halkjær Jytte, Overvad Kim, Tjønneland Anne
1 Danish Cancer Society Research Center , Copenhagen, Denmark .
Biopreserv Biobank. 2013 Aug;11(4):206-10. doi: 10.1089/bio.2013.0029. Epub 2013 Aug 6.
We here describe the July 2011 flooding of the Danish Diet, Cancer and Health biobank, which contained blood and urine samples and fat tissue biopsies from 57,053 Danes. We use this as a starting point to detail empirically derived knowledge on how to best restore and secure a biobank and test the quality of flooded samples; a process which has taken place over the subsequent 2-year period. The aim is to generate a framework for such a restoration process, which may be useful in relation to future biobank floods. The framework includes four steps: 1) freeze-drying of the samples, 2) cleaning and reorganization of the samples, 3) quality testing of the samples, and 4) documentation and communication. Furthermore, we present general experiences derived with regard to planning, financing, and stakeholder contact in such a restoration process.
我们在此描述2011年7月丹麦饮食、癌症与健康生物样本库遭遇的洪水事件，该生物样本库保存有来自57053名丹麦人的血液、尿液样本以及脂肪组织活检样本。我们以此为起点，详细阐述通过实证得出的关于如何最佳地恢复和保障生物样本库以及检测受洪水影响样本质量的知识；这一过程在随后的两年里展开。目的是生成一个此类恢复过程的框架，这对于未来生物样本库遭遇洪水事件可能会有所帮助。该框架包括四个步骤：1）样本冷冻干燥，2）样本清理与重新整理，3）样本质量检测，4）记录与沟通。此外，我们还介绍了在这样一个恢复过程中有关规划、资金筹措以及与利益相关者联系方面所获得的一般经验。
