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机器人辅助手术在二尖瓣疾病中的价值。

Value of robotically assisted surgery for mitral valve disease.

机构信息

Heart and Vascular Institute, Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio2Heart and Vascular Institute, Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Abu Dhabi, United Arab Emirates.

Heart and Vascular Institute, Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.

出版信息

JAMA Surg. 2014 Jul;149(7):679-86. doi: 10.1001/jamasurg.2013.5680.

Abstract

IMPORTANCE

The value of robotically assisted surgery for mitral valve disease is questioned because the high cost of care associated with robotic technology may outweigh its clinical benefits.

OBJECTIVE

To investigate conditions under which benefits of robotically assisted surgery mitigate high technology costs.

DESIGN, SETTING, AND PARTICIPANTS: Clinical cohort study at a large multispecialty academic medical center comparing costs of robotically assisted surgery with 3 contemporaneous conventional surgical approaches for degenerative mitral valve disease. From January 1, 2006, through December 31, 2010, a total of 1290 patients with a mean (SD) age of 57 (11) years underwent mitral valve repair for regurgitation from posterior leaflet prolapse. Robotically assisted surgery was performed in 473 patients, complete sternotomy in 227, partial sternotomy in 349, and anterolateral thoracotomy in 241. Comparisons were based on intent to treat, with 3 propensity-matched groups formed based on demographics, symptoms, cardiac and noncardiac comorbidities, valve pathophysiologic disorders, and echocardiographic measurements: robotic vs sternotomy (198 pairs) vs partial sternotomy (293 pairs) vs thoracotomy (224 pairs).

INTERVENTIONS

Mitral valve repair.

MAIN OUTCOMES AND MEASURES

Cost of care (expressed as robotic capital investment, maintenance of equipment, and direct technical hospital costs) and benefit of care (based on differences in recovery time).

RESULTS

Cost of care (median [15th and 85th percentiles]) for robotically assisted surgery exceeded that of alternative approaches by 26.8% (-5.3% and 67.9%), 32.1% (-6.1% and 69.6%), and 20.7% (-2.4% and 48.4%) for complete sternotomy, partial sternotomy, and anterolateral thoracotomy, respectively. Higher operative costs were partially offset by lower postoperative costs and earlier return to work: a median (15th and 85th percentiles) of 35 (19 and 63) days for robotically assisted surgery, 49 (21 and 109) days for complete sternotomy, 56 (30 and 119) days for partial sternotomy, and 42 (18 and 90) days for anterolateral thoracotomy. Resulting net differences (median [15th and 85th percentiles]) in the cost of robotic surgery vs the 3 alternatives were 15.6% (-14.7% and 55.1%), 15.7% (-19.4% and 51.2%), and 14.8% (-7.4% and 43.6%), respectively. Beyond a volume threshold of 55 to 100 robotically assisted operations per year, distribution of the cost of this technology broadly overlapped those of conventional approaches.

CONCLUSIONS AND RELEVANCE

In exchange for higher procedural costs, robotically assisted surgery for mitral valve repair offers the clinical benefit of least-invasive surgery, lowest postoperative cost, and fastest return to work. The value of robotically assisted surgery that is similar to that of conventional approaches can be realized only in high-volume centers.

摘要

重要性

机器人辅助手术治疗二尖瓣疾病的价值受到质疑,因为与机器人技术相关的高昂医疗成本可能超过其临床获益。

目的

研究在何种情况下机器人辅助手术的获益可以减轻高科技成本。

设计、环境和参与者:在一家大型多专科学术医疗中心进行的退行性二尖瓣疾病的机器人辅助手术与 3 种同期常规手术方法的成本比较的临床队列研究。2006 年 1 月 1 日至 2010 年 12 月 31 日,共有 1290 名平均(标准差)年龄为 57(11)岁的患者因后叶脱垂性二尖瓣反流而行二尖瓣修复术。473 例患者接受机器人辅助手术,227 例行全胸骨切开术,349 例行部分胸骨切开术,241 例行前外侧开胸术。比较基于意向治疗,基于人口统计学、症状、心脏和非心脏合并症、瓣膜病理生理障碍和超声心动图测量,形成了 3 个基于倾向评分匹配的组:机器人与胸骨切开术(198 对)、部分胸骨切开术(293 对)和前外侧开胸术(224 对)。

干预措施

二尖瓣修复术。

主要观察指标和测量方法

医疗费用(表示为机器人资本投资、设备维护和直接技术医院费用)和医疗效益(基于恢复时间的差异)。

结果

机器人辅助手术的医疗费用(中位数[第 15 和第 85 百分位数])比替代方法分别高出 26.8%(-5.3%至 67.9%)、32.1%(-6.1%至 69.6%)和 20.7%(-2.4%至 48.4%),分别为全胸骨切开术、部分胸骨切开术和前外侧开胸术。较高的手术费用部分被较低的术后费用和更早的返工所抵消:机器人辅助手术的中位数(第 15 和第 85 百分位数)为 35(19 至 63)天,全胸骨切开术为 49(21 至 109)天,部分胸骨切开术为 56(30 至 119)天,前外侧开胸术为 42(18 至 90)天。机器人手术与 3 种替代方案相比,净成本差异(中位数[第 15 和第 85 百分位数])分别为 15.6%(-14.7%至 55.1%)、15.7%(-19.4%至 51.2%)和 14.8%(-7.4%至 43.6%)。在每年 55 至 100 例机器人辅助手术的容量阈值以上,该技术的成本分布与常规方法广泛重叠。

结论和相关性

机器人辅助二尖瓣修复术的临床获益为微创、最低术后成本和最快恢复工作,可换取更高的手术成本。只有在高容量中心才能实现与传统方法相似的机器人辅助手术的价值。

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