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45 至 74 岁韩国人群亚甲基四氢叶酸还原酶 677 基因型特异性血浆同型半胱氨酸和血清叶酸浓度参考值：全州研究。

Methylenetetrahydrofolate reductase 677 genotype-specific reference values for plasma homocysteine and serum folate concentrations in korean population aged 45 to 74 years: the Namwon study.

机构信息

Department of Preventive Medicine, Chonnam National University Medical School and Research Institute of Medical Sciences, Gwangju, Korea. ; Vanderbilt Epidemiology Center, Institute of Medicine and Public Health, Vanderbilt University School of Medicine, Nashville, TN, USA.

Department of Preventive Medicine & Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, Iksan, Korea.

出版信息

J Korean Med Sci. 2014 May;29(5):743-7. doi: 10.3346/jkms.2014.29.5.743. Epub 2014 Apr 25.

DOI:10.3346/jkms.2014.29.5.743
PMID:24851035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4024951/
Abstract

The reference interval for plasma total homocysteine (tHcy) and serum folate concentrations were estimated. Total of 3,154 reference individuals (1,029 men and 2,125 women) were selected based on stringent exclusion criteria. For plasma tHcy concentration (µM/L), reference values (median [5-95 percentile]) were 7.72 (5.03 to 13.80) and 6.09 (3.95-10.19) in men and women, respectively. For serum folate concentration (nM/L), reference values were 23.71 (11.73-38.44) and 28.95 (15.23-40.44) in men and women, respectively. The tHcy levels of both genders in the present study were lower than those in previous reports from other countries and Korea.

摘要

本研究中，男性和女性的血浆总同型半胱氨酸（tHcy）水平均低于其他国家和韩国以往报告中的水平。分别对血浆总同型半胱氨酸（tHcy）浓度（µM/L）和血清叶酸浓度（nM/L）的参考区间进行了估计。基于严格的排除标准，共选择了 3154 名参考个体（男性 1029 人，女性 2125 人）。男性和女性的血浆 tHcy 浓度参考值（中位数[5-95 分位数]）分别为 7.72（5.03 至 13.80）和 6.09（3.95 至 10.19）。血清叶酸浓度参考值分别为 23.71（11.73-38.44）和 28.95（15.23-40.44）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4453/4024951/2741d859c472/jkms-29-743-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4453/4024951/2741d859c472/jkms-29-743-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4453/4024951/2741d859c472/jkms-29-743-g001.jpg

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