Vázquez-González Margarita, Carrillo-Carrion Carolina
University of Santiago de Compostela, Inorganic Chemistry Department, Faculty of Pharmacy, Galicia 5706, SpainbPhilipps University of Marburg, Fachbereich Physik, Renthof 7, Marburg 35037, Germany.
Philipps University of Marburg, Fachbereich Physik, Renthof 7, Marburg 35037, Germany.
J Biomed Opt. 2014;19(10):101503. doi: 10.1117/1.JBO.19.10.101503.
Heavy metal contamination is one of the major concerns to human health because these substances are toxic and retained by the ecological system. Therefore, in recent years, there has been a pressing need for fast and reliable methods for the analysis of heavy metal ions in environmental and biological samples. Quantum dots (QDs) have facilitated the development of sensitive sensors over the past decade, due to their unique photophysical properties, versatile surface chemistry and ligand binding ability, and the possibility of the encapsulation in different materials or attachment to different functional materials, while retaining their native luminescence property. This paper comments on different sensing strategies with QD for the most toxic heavy metal ions (i.e., cadmium, Cd2+; mercury, Hg2+; and lead, Pb2+). Finally, the challenges and outlook for the QD-based sensors for heavy metals ions are discussed.
重金属污染是人类健康的主要担忧之一，因为这些物质具有毒性且会被生态系统留存。因此，近年来，迫切需要快速可靠的方法来分析环境和生物样品中的重金属离子。在过去十年中，量子点（QDs）因其独特的光物理性质、多样的表面化学性质和配体结合能力，以及能够封装在不同材料中或附着于不同功能材料上同时保持其固有发光特性，推动了灵敏传感器的发展。本文评述了利用量子点检测最具毒性的重金属离子（即镉，Cd2+；汞，Hg2+；铅，Pb2+）的不同传感策略。最后，讨论了基于量子点的重金属离子传感器面临的挑战和前景。
