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[儿童肺转移瘤的外科治疗]

[Surgery of lung metastasis in childhood].

作者信息

Rivilla Parra F, Gámez Arance M, Fernández Sánchez A, González Sánchez M C, González Utrilla J

出版信息

Cir Pediatr. 1989 Apr;2(2):58-60.

PMID:2485669
Abstract

From 1975 to 1987, we have operated 20 cases with lung metastases. They were 12 females and 8 males with ages between 1,6 and 12 years old (average of 5 years). The histology of the primary neoplasia was: 13 cases with Wilms' Tumors, 3 cases with Ewing's Sarcoma and 1 case with Neuroblastoma, Rhabdomiosarcoma, Hepatoblastoma and Neuroectodermic Tumor of Askin. We found 38 metastases and there were performed through a Thoracotomy 28 wedge resection, 7 pulmonary lobectomies and 3 biopsies. The operative mortality was 0%. The most frequent location of the lesion were on medium and lower lobule of the right lung. The survival was 70% (14 cases) after 4 years of average of the follow up. The survival for Wilms Tumors was 61% (8 cases) and all patients with Ewing's Sarcoma, Rhabdomiosarcoma, Neuroblastoma and Neuroectodermic Tumor of Askin were alive. The Thoracotomy is a useful method for therapy of tumors in children with lung metastases associated to chemotherapy and radiotherapy.

摘要

1975年至1987年,我们共为20例肺转移患者实施了手术。其中女性12例,男性8例,年龄在1.6岁至12岁之间(平均5岁)。原发肿瘤的组织学类型为:肾母细胞瘤13例,尤因肉瘤3例,神经母细胞瘤、横纹肌肉瘤、肝母细胞瘤及阿金神经外胚层肿瘤各1例。我们共发现38处转移灶,其中28处通过开胸手术行楔形切除术,7处行肺叶切除术,3处取活检。手术死亡率为0%。病变最常见的部位是右肺的中、下叶。平均随访4年后,生存率为70%(14例)。肾母细胞瘤的生存率为61%(8例),所有尤因肉瘤、横纹肌肉瘤、神经母细胞瘤及阿金神经外胚层肿瘤患者均存活。开胸手术是治疗儿童肺转移瘤并联合化疗和放疗的一种有效方法。

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