使用颊黏膜微核细胞分析法对牙科放射学领域专业人员的辐射风险评估。
Radiation risk assessment in professionals working in dental radiology area using buccal micronucleus cytome assay.
作者信息
Sadatullah Syed, Dawasaz Ali Azhar, Luqman Master, Assiry Ali A, Almeshari Ahmed A, Togoo Rafi Ahmad
机构信息
Assistant Professor, Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, King Khalid University Abha, Saudi Arabia, Phone: 00966502584456, e-mail: dr.sadat@ hotmail.com.
Assistant Professor, Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, King Khalid University Abha, Saudi Arabia.
出版信息
J Contemp Dent Pract. 2013 Nov 1;14(6):1024-7. doi: 10.5005/jp-journals-10024-1444.
OBJECTIVE
The aim of this study was to assess the incidence of micronuclei (MN) in buccal mucosal cells of professionals working in radiology area to determine the risk of stochastic effects of radiation.
MATERIALS AND METHODS
All the professionals and students working in King Khalid University - College of Dentistry radiology area were included in the Risk Group (RG = 27). The Control Group (CG = 27) comprised of healthy individual matching the gender and age of the RG. Buccal mucosal scraping from all the 54 subjects of RG and CG were stained with Papanicolaou stain and observed under oil immersion lens (×100) for the presence of micronuclei (MN) in the exfoliated epithelial cells.
RESULTS
There was no significant difference between the incidence of MN in RG and CG (p = >0.05) using t-test.
CONCLUSION
Routine radiation protection protocol does minimize the risk of radiation induced cytotoxicity, however, screening of professionals should be carried out at regular intervals.
目的
本研究旨在评估放射科专业人员颊黏膜细胞中微核（MN）的发生率，以确定辐射随机效应的风险。
材料与方法
所有在哈利德王大学牙科学院放射科工作的专业人员和学生被纳入风险组（RG = 27）。对照组（CG = 27）由年龄和性别与风险组相匹配的健康个体组成。对风险组和对照组的54名受试者的颊黏膜刮片进行巴氏染色，并在油镜（×100）下观察脱落上皮细胞中微核（MN）的存在情况。
结果
使用t检验，风险组和对照组中微核的发生率无显著差异（p = >0.05）。
结论
常规的辐射防护方案确实能将辐射诱导的细胞毒性风险降至最低，然而，仍应定期对专业人员进行筛查。
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