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Intensive Care Med. 2012 Dec;38(12):1946-54. doi: 10.1007/s00134-012-2720-z. Epub 2012 Oct 12.
2
High-dose intravenous immunoglobulins: a promising therapeutic approach for idiopathic systemic capillary leak syndrome.大剂量静脉注射免疫球蛋白:治疗特发性系统性毛细血管渗漏综合征的一种有前景的方法。
BMJ Case Rep. 2011 May 3;2011:bcr1220103599. doi: 10.1136/bcr.12.2010.3599.
3
Idiopathic systemic capillary leak syndrome (Clarkson's disease): the Mayo clinic experience.特发性全身性毛细血管渗漏综合征(克拉克森病):梅奥诊所的经验。
Mayo Clin Proc. 2010 Oct;85(10):905-12. doi: 10.4065/mcp.2010.0159. Epub 2010 Jul 15.
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Aspergillosis.曲霉病
N Engl J Med. 2009 Apr 30;360(18):1870-84. doi: 10.1056/NEJMra0808853.
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Hydrocortisone therapy for patients with septic shock.氢化可的松治疗感染性休克患者。
N Engl J Med. 2008 Jan 10;358(2):111-24. doi: 10.1056/NEJMoa071366.
6
Invasive aspergillosis in the intensive care unit.重症监护病房中的侵袭性曲霉病
Clin Infect Dis. 2007 Jul 15;45(2):205-16. doi: 10.1086/518852. Epub 2007 Jun 13.
7
Idiopathic systemic capillary leak syndrome (SCLS): case report and systematic review of cases reported in the last 16 years.特发性系统性毛细血管渗漏综合征(SCLS):病例报告及过去16年报道病例的系统综述
Intern Med. 2007;46(12):899-904. doi: 10.2169/internalmedicine.46.6129. Epub 2007 Jun 15.
8
Initial CT manifestations of invasive pulmonary aspergillosis in 45 non-HIV immunocompromised patients: association with patient outcome?45例非HIV免疫功能低下患者侵袭性肺曲霉病的初始CT表现:与患者预后的关联?
Eur J Radiol. 2005 Sep;55(3):437-44. doi: 10.1016/j.ejrad.2005.01.001. Epub 2005 Jan 28.
9
Glucocorticoids and invasive fungal infections.糖皮质激素与侵袭性真菌感染。
Lancet. 2003 Nov 29;362(9398):1828-38. doi: 10.1016/S0140-6736(03)14904-5.
10
Cyclical edema and shock due to increased capillary permeability.由于毛细血管通透性增加导致的周期性水肿和休克。
Am J Med. 1960 Aug;29:193-216. doi: 10.1016/0002-9343(60)90018-8.

一名患有特发性系统性毛细血管渗漏综合征的患者发生侵袭性肺曲霉病。

Invasive pulmonary aspergillosis in a patient presenting with idiopathic systemic capillary leak syndrome.

作者信息

Hayama Manabu, Shime Nobuaki, Mio Tadashi

机构信息

Department of Respiratory Medicine, National Hospital Organization Kyoto Medical Center, Kyoto-shi, Kyoto, Japan.

Department of Emergency and Critical Care Medicine, National Hospital Organization Kyoto Medical Center, Kyoto-shi, Kyoto, Japan.

出版信息

BMJ Case Rep. 2014 May 23;2014:bcr2014203764. doi: 10.1136/bcr-2014-203764.

DOI:10.1136/bcr-2014-203764
PMID:24859554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4039934/
Abstract

A 54-year-old man presented to our emergency department with fever and dyspnoea. He required vigorous haemodynamic support and mechanical ventilation for hypotensive distributive shock with hypoalbuminaemia, haemoconcentration, rhabdomyolysis and acute renal failure, consistent with idiopathic systemic capillary leak syndrome. Left lung consolidation and hypoxaemia were observed 6 days after admission. Sputum smear revealed the presence of acute angled branching hyphae, consistent with a diagnosis of invasive pulmonary aspergillosis. Antifungal therapy was administered and mechanical ventilation discontinued on day 66. The patient recovered and was discharged from the hospital on day 185.

摘要

一名54岁男性因发热和呼吸困难前来我院急诊科就诊。他因伴有低白蛋白血症、血液浓缩、横纹肌溶解和急性肾衰竭的低血压性分布性休克,需要积极的血流动力学支持和机械通气,这与特发性系统性毛细血管渗漏综合征相符。入院6天后观察到左肺实变和低氧血症。痰涂片显示存在急性成角分支菌丝,符合侵袭性肺曲霉病的诊断。给予抗真菌治疗,并于第66天停止机械通气。患者康复,并于第185天出院。