[Recent evolution of the epidemiological profile of extended-spectrum β-lactamase producing uropathogenic enterobacteria in Marrakech, Morocco].
作者信息
El Bouamri M C, Arsalane L, Kamouni Y, Berraha M, Zouhair S
机构信息
Laboratoire de bactériologie et virologie, hôpital militaire et universitaire Avicenne, Marrakech, Maroc; Faculté de médecine et de pharmacie, université Mohammed V-Souissi-Rabat, Souissi-Rabat, Maroc.
Laboratoire de bactériologie et virologie, hôpital militaire et universitaire Avicenne, Marrakech, Maroc; Faculté de médecine et de pharmacie, université Cadi Ayyad-Marrakech, Marrakech, Maroc.
出版信息
Prog Urol. 2014 Jun;24(7):451-5. doi: 10.1016/j.purol.2013.11.010. Epub 2014 Jan 6.
INTRODUCTION
Urinary tract infection by extended-spectrum β-lactamase producing enterobacteriaceae (ESBL-E) is a growing infection risk and may even lead in many cases to therapeutic impasses because of their multidrug resistance.
AIM OF THE STUDY
Follow, over a 5-year period, the evolution of the epidemiological profile of uropathogenic ESBL-E and describe their current level of antibiotic resistance.
MATERIALS AND METHODS
A retrospective work was made over a period of 5 years (from 1st January 2008 to 31st December 2012). It focused on all the ESBL-E strains isolated from all the urinary samples at the microbiology laboratory of Avicenne hospital, Marrakech (Morocco).
RESULTS
We noticed in 5 years, an important increase in the prevalence of ESBL-E. The higher prevalence of ESBL-E (51%) was recorded in the urology department. The study of the antibiotic resistance of the ESBL-E had shown antibiotic co-resistances to the ciprofloxacin (82%), to sulfamethoxazole-trimethropim (85%), to gentamicin (74%), to amikacine (51%). Our results also showed, for the first time in our region, an emergence in the resistance of enterobacteria producing ESBL to imipenem (10%).
CONCLUSION
The significant increase in the prevalence of ESBL-E has become a concern at the hospitals and in community medicine as well. The study of the resistance of ESBL-E strains antibiotics showed high rates of co-resistance to antibiotics, including the usual urology molecules.
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