Anderström C, Johansson S L, Pettersson S, Wahlqvist L
Sahlgrenska sjukhuset, Göteborg, Sweden.
J Urol. 1989 Aug;142(2 Pt 1):280-3. doi: 10.1016/s0022-5347(17)38730-x.
We reviewed 49 patients with urothelial tumors of the ureter: 33 male and 16 female patients with a mean age of 64.8 and 66.3 years, respectively. Median followup was 83 months. Gross hematuria was present in 29 patients and a silent kidney was found in 21. The majority of the tumors were in the distal ureter and approximately 50 per cent of the patients had synchronous or asynchronous urothelial tumors. The majority of the patients had low grade, low stage tumors (75 per cent). A total of 21 patients underwent local resection and none died of tumor. Only 1 of these 21 patients had an ipsilateral recurrence. Nephroureterectomy was performed in 24 patients and 5 of them died of ureteral tumor, including 4 in whom periureteral tumor growth initially was recorded. The prognosis of patients with papillomas or grades 1 to 3, stages Pa to P1 ureteral tumors was excellent and a conservative approach is recommended for these patients. Abuse of combination analgesics containing phenacetin, phenazone and caffeine may be a risk factor for development of ureteral tumors.
我们回顾了49例输尿管尿路上皮肿瘤患者：33例男性和16例女性，平均年龄分别为64.8岁和66.3岁。中位随访时间为83个月。29例患者出现肉眼血尿，21例发现无症状肾。大多数肿瘤位于输尿管远端，约50%的患者有同步或异时性尿路上皮肿瘤。大多数患者为低级别、低分期肿瘤（75%）。共有21例患者接受了局部切除，无一例死于肿瘤。这21例患者中只有1例同侧复发。24例患者接受了肾输尿管切除术，其中5例死于输尿管肿瘤，包括4例最初记录有输尿管周围肿瘤生长的患者。乳头状瘤或1至3级、Pa至P1期输尿管肿瘤患者的预后良好，建议对这些患者采取保守治疗方法。滥用含非那西丁、保泰松和咖啡因的复方镇痛药可能是输尿管肿瘤发生的一个危险因素。
