Ferreira Sabrina Maria Saueia, Navarro Anderson Marliere, Magalhães Patrícia Künzle Ribeiro, Maciel Léa Maria Zanini
Divisão de Endocrinologia, Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Divisão de Nutrição, Departamento de Clínica Médica, FMRP, USP, Ribeirão Preto, SP, Brazil.
Arq Bras Endocrinol Metabol. 2014 Apr;58(3):282-7. doi: 10.1590/0004-2730000002979.
The intake of adequate amounts of iodine during pregnancy is essential for the neurological development of the fetus. The aim of this study was to assess iodine nutrition status in pregnant women from the state of São Paulo, Brazil.
We analyzed urinary iodine concentration (UIC) in 191 pregnant and 58 non-pregnant women matched by age. We used the World Health Organization criteria to define sufficient iodine supply (median UIC: 150-249 µg/L among pregnant women, and 100-199 µg/L for non-pregnant women).
Median UIC of the pregnant women studied was lower than the recommended value (median = 137.7 µg/L, 95% CI = 132.9 - 155.9), while non-pregnant women had UIC levels within the appropriate range (median = 190 μg/L; 95% IC = 159.3-200.1). UIC was below 150 µg/L in 57% of the pregnant women.
Although a larger sample is needed to consolidate these findings, these results raise concerns about the adequacy of the iodine supply of pregnant women in Brazil, especially considering the new determinations of the Brazilian government, which have recently reduced the concentrations of iodine in table salt to 15-45 mg/kg of salt.
孕期摄入足够量的碘对胎儿的神经发育至关重要。本研究旨在评估巴西圣保罗州孕妇的碘营养状况。
我们分析了191名孕妇和58名年龄匹配的非孕妇的尿碘浓度（UIC）。我们采用世界卫生组织的标准来定义充足的碘供应（孕妇的UIC中位数：150 - 249μg/L，非孕妇为100 - 199μg/L）。
所研究孕妇的UIC中位数低于推荐值（中位数 = 137.7μg/L，95%置信区间 = 132.9 - 155.9），而非孕妇的UIC水平在适当范围内（中位数 = 190μg/L；95%置信区间 = 159.3 - 200.1）。57%的孕妇UIC低于150μg/L。
尽管需要更大的样本量来巩固这些发现，但这些结果引发了对巴西孕妇碘供应充足性的担忧，特别是考虑到巴西政府最近的新规定，即已将食盐中的碘浓度降至15 - 45mg/kg盐。
