Bilgilisoy Filiz Meral, Filiz Serkan, Baran Rıza Taner, Çakır Tuncay, Koldaş Doğan Şebnem, Parlak Mesut, Toraman Naciye Füsun
Department of Physical Medicine and Rehabilitation, Health Sciences University, Antalya Training and Research Hospital, Antalya, Turkey.
Department of Pediatric Allergy and Immunology, Health Sciences University, Antalya Training and Research Hospital, Antalya, Turkey.
Turk J Phys Med Rehabil. 2018 Mar 12;64(3):198-204. doi: 10.5606/tftrd.2018.2265. eCollection 2018 Sep.
This study aims to investigate the frequency and severity of restless legs syndrome (RLS) and its relationship with sleep quality in children with allergic rhinitis (AR) with the hypothesis that comorbid RLS may be an additional causative factor of sleep disturbances in pediatric AR.
A total of 143 children with AR (aged 8-18 years) and 144 healthy control subjects (aged 8-18 years) were included. The diagnosis of AR was established on history, clinical examination and skin prick test according to the Allergic Rhinitis and its Impact on Asthma guidelines. Presence of RLS was determined using the International RLS study group (IRLSSG) criteria. The severity of RLS was assessed using the IRLSSG rating scale. Sleep quality was evaluated by Pittsburgh Sleep Quality Index (PSQI).
Thirteen patients (9.1%) in AR group, and six children (4.2%) in control group had RLS (p=0.159). The frequency of RLS in AR group was higher than two folds when compared to the control group; however, the difference was not statistically significant. Restless legs syndrome severity score was significantly higher in AR group than control group (15.00 [11-20] and 11.00 [10-16] respectively, p=0.046). Total PSQI scores were similar between groups. Also, no significant differences were observed in total PSQI scores of AR patients with or without RLS.
Restless legs syndrome was not more common but was more severe in children with AR. There was no evidence that RLS has an obvious effect on sleep quality in children with AR.
本研究旨在调查变应性鼻炎（AR）患儿不安腿综合征（RLS）的发生率和严重程度及其与睡眠质量的关系，假设共病RLS可能是小儿AR睡眠障碍的另一个致病因素。
共纳入143例AR患儿（8 - 18岁）和144例健康对照者（8 - 18岁）。根据变应性鼻炎及其对哮喘的影响指南，通过病史、临床检查和皮肤点刺试验确诊AR。采用国际不安腿综合征研究组（IRLSSG）标准确定RLS的存在。使用IRLSSG评分量表评估RLS的严重程度。通过匹兹堡睡眠质量指数（PSQI）评估睡眠质量。
AR组有13例患者（9.1%），对照组有6例儿童（4.2%）患有RLS（p = 0.159）。AR组RLS的发生率比对照组高两倍多；然而，差异无统计学意义。AR组不安腿综合征严重程度评分显著高于对照组（分别为15.00 [11 - 20]和11.00 [10 - 16]，p = 0.046）。两组间PSQI总分相似。此外，有或无RLS的AR患者PSQI总分均未观察到显著差异。
不安腿综合征在AR患儿中并不更常见，但更严重。没有证据表明RLS对AR患儿的睡眠质量有明显影响。
