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不安腿综合征在纤维肌痛女性患者中很常见。

Restless legs syndrome is common among female patients with fibromyalgia.

作者信息

Stehlik Romana, Arvidsson Lennart, Ulfberg Jan

机构信息

Sleep Disorders Center, Avesta Hospital, Avesta, Sweden.

出版信息

Eur Neurol. 2009;61(2):107-11. doi: 10.1159/000180313. Epub 2008 Dec 9.

Abstract

BACKGROUND

The prevalence of restless legs syndrome (RLS) among the general population is 2-15%, and with fibromyalgia syndrome (FMS) 2%. Both RLS and FMS are more common among women. The aim of our study was to evaluate the prevalence of RLS in a group of female patients diagnosed with FMS and to compare the occurrence of symptoms of daytime sleepiness and experienced sleep disorders between fibromyalgia patients with or without RLS.

METHOD

Three hundred and thirty-two female patients, 20-60 years old, diagnosed with FMS at Skonviks Rehab between 2002 and 2006, answered a questionnaire mailed to their home address. The questionnaire consisted of the international RLS study group criteria as well as of questions concerning symptoms of insomnia and daytime sleepiness measured according to the Epworth Sleepiness Scale.

RESULTS

Nearly 64% of the women were also suffering from RLS. More patients suffering from both RLS and FMS were affected by problems of initiating and maintaining sleep than those suffering from FMS only. More patients suffering from both RLS and FMS did not feel refreshed on awakening compared with those suffering from FMS without RLS. The patients with concomitant RLS and FMS were more often hypersomnolent than those suffering from FMS only.

CONCLUSION

This study shows that 64% of a group of female patients diagnosed with fibromyalgia also concurrently suffered from RLS. Compared with patients who suffer from FMS only, patients with both FMS and RLS more often experience sleep disturbances and pronounced daytime sleepiness.

摘要

背景

不安腿综合征(RLS)在普通人群中的患病率为2% - 15%,在纤维肌痛综合征(FMS)患者中的患病率为2%。RLS和FMS在女性中更为常见。我们研究的目的是评估一组被诊断为FMS的女性患者中RLS的患病率,并比较伴有或不伴有RLS的纤维肌痛患者日间嗜睡症状和经历的睡眠障碍的发生率。

方法

2002年至2006年间在Skonviks康复中心被诊断为FMS的332名20 - 60岁女性患者,回答了邮寄到她们家庭住址的问卷。问卷包括国际RLS研究组标准以及根据爱泼华嗜睡量表测量的失眠和日间嗜睡症状相关问题。

结果

近64%的女性同时患有RLS。与仅患有FMS的患者相比,同时患有RLS和FMS的患者在入睡和维持睡眠方面存在更多问题。与不伴有RLS的FMS患者相比,同时患有RLS和FMS的患者醒来时感觉不清醒的情况更多。伴有RLS和FMS的患者比仅患有FMS的患者更常出现嗜睡。

结论

本研究表明,一组被诊断为纤维肌痛的女性患者中有64%同时患有RLS。与仅患有FMS的患者相比,同时患有FMS和RLS的患者更常经历睡眠障碍和明显的日间嗜睡。

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