Department of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599-3287, USA.
Nanotechnology. 2014 Jun 20;25(24):245704. doi: 10.1088/0957-4484/25/24/245704. Epub 2014 May 28.
For imaging human breast cancer, digital breast tomosynthesis (DBT) has been shown to improve image quality and breast cancer detection in comparison to two-dimensional (2D) mammography. Current DBT systems have limited spatial resolution and lengthy scan times. Stationary DBT (s-DBT), utilizing an array of carbon nanotube (CNT) field emission x-ray sources, provides increased spatial resolution and potentially faster imaging than current DBT systems. This study presents the results of detailed evaluations of CNT cathodes for x-ray breast imaging tasks. The following were investigated: high current, long-term stability of CNT cathodes for DBT; feasibility of using CNT cathodes to perform a 2D radiograph function; and cathode performance through several years of imaging. Results show that a breast tomosynthesis system using CNT cathodes could run far beyond the experimentally tested lifetime of one to two years. CNT cathodes were found capable of producing higher currents than typical DBT would require, indicating that the s-DBT imaging time can be further reduced. The feasibility of using a single cathode of the s-DBT tube to perform 2D mammography in 4 s was demonstrated. Over the lifetime of the prototype s-DBT system, it was found that both cathode performance and transmission rate were stable and consistent.
对于人体乳腺癌成像,与二维(2D)乳房 X 光摄影相比,数字乳腺断层合成(DBT)已被证明可改善图像质量和乳腺癌检测。目前的 DBT 系统空间分辨率有限,扫描时间长。使用碳纳米管(CNT)场致发射 X 射线源的固定 DBT(s-DBT)提供了比当前 DBT 系统更高的空间分辨率和潜在更快的成像速度。本研究介绍了用于 X 射线乳房成像任务的 CNT 阴极的详细评估结果。以下是研究的内容:用于 DBT 的 CNT 阴极的大电流、长期稳定性;使用 CNT 阴极执行 2D 射线照相功能的可行性;以及多年成像的阴极性能。结果表明,使用 CNT 阴极的乳腺断层合成系统的运行时间远远超过了一到两年的实验测试寿命。研究发现,CNT 阴极产生的电流高于典型 DBT 所需的电流,这表明 s-DBT 成像时间可以进一步缩短。证明了使用 s-DBT 管的单个阴极在 4 秒内执行 2D 乳房 X 光摄影的可行性。在原型 s-DBT 系统的使用寿命内,发现阴极性能和传输率稳定且一致。