Department of Applied Physical Sciences, University of North Carolina at Chapel Hill, 120 E. Cameron Avenue, Chapel Hill, 27599, USA.
Department of Physics and Astronomy, University of North Carolina at Chapel Hill, 120 E. Cameron Avenue, Chapel Hill, 27599, USA.
Med Phys. 2017 Sep;44(9):4482-4495. doi: 10.1002/mp.12393. Epub 2017 Jul 25.
The aim of this study was to characterize a new generation stationary digital breast tomosynthesis system with higher tube flux and increased angular span over a first generation system.
The linear CNT x-ray source was designed, built, and evaluated to determine its performance parameters. The second generation system was then constructed using the CNT x-ray source and a Hologic gantry. Upon construction, test objects and phantoms were used to characterize system resolution as measured by the modulation transfer function (MTF), and artifact spread function (ASF).
The results indicated that the linear CNT x-ray source was capable of stable operation at a tube potential of 49 kVp, and measured focal spot sizes showed source-to-source consistency with a nominal focal spot size of 1.1 mm. After construction, the second generation (Gen 2) system exhibited entrance surface air kerma rates two times greater the previous s-DBT system. System in-plane resolution as measured by the MTF is 7.7 cycles/mm, compared to 6.7 cycles/mm for the Gen 1 system. As expected, an increase in the z-axis depth resolution was observed, with a decrease in the ASF from 4.30 mm to 2.35 mm moving from the Gen 1 system to the Gen 2 system as result of an increased angular span.
The results indicate that the Gen 2 stationary digital breast tomosynthesis system, which has a larger angular span, increased entrance surface air kerma, and faster image acquisition time over the Gen 1 s-DBT system, results in higher resolution images. With the detector operating at full resolution, the Gen 2 s-DBT system can achieve an in-plane resolution of 7.7 cycles per mm, which is better than the current commercial DBT systems today, and may potentially result in better patient diagnosis.
本研究旨在对新一代具有更高管电流和更大角度覆盖范围的静态数字乳腺断层合成系统进行特征描述,该系统与第一代系统相比。
设计、构建并评估了线性 CNT X 射线源,以确定其性能参数。然后,使用 CNT X 射线源和 Hologic 龙门架构建第二代系统。在构建完成后,使用测试物体和体模来表征系统分辨率,这是通过调制传递函数(MTF)和伪影传播函数(ASF)来测量的。
结果表明,线性 CNT X 射线源能够在 49kVp 的管电压下稳定运行,并且测量的焦点尺寸显示出与标称焦点尺寸 1.1mm 的源到源一致性。构建完成后,第二代(Gen 2)系统的入口表面空气比释动能率比前一代 s-DBT 系统高两倍。通过 MTF 测量的系统平面内分辨率为 7.7 个周期/mm,而第一代系统为 6.7 个周期/mm。如预期的那样,由于角度覆盖范围的增加,观察到 z 轴深度分辨率提高,ASF 从第一代系统的 4.30mm 减小到第二代系统的 2.35mm。
结果表明,第二代静态数字乳腺断层合成系统具有更大的角度覆盖范围、更大的入口表面空气比释动能和比第一代 s-DBT 系统更快的图像采集时间,从而产生更高分辨率的图像。随着探测器以全分辨率运行,第二代 s-DBT 系统可以实现 7.7 个周期/mm 的平面内分辨率,这优于当前的商业 DBT 系统,并且可能会提高患者的诊断效果。