Rajkumar S, Thara R
Madras Medical College, India.
Schizophr Res. 1989 Jul-Oct;2(4-5):403-9. doi: 10.1016/0920-9964(89)90033-9.
96 first episode schizophrenic patients were included for a prospective follow-up study on factors affecting course and outcome of schizophrenia. Feighner's diagnostic criteria were used for inclusion and a yearly assessment was made using the Present State Examination and the Personal and Psychiatric History Schedule. At the end of 3 years, 64 patients had been followed up. Of these, 38 patients had one or more relapses. A comparison of the relapsing group with the non-relapsers revealed certain variables to be significantly associated with relapses. Some of these were regularity of follow-up, presence of affective symptoms and self-neglect and lack of social contacts. The importance of recognising these factors in order to prevent relapses in schizophrenia is discussed.
96例首发精神分裂症患者被纳入一项关于影响精神分裂症病程和结局因素的前瞻性随访研究。采用费格纳诊断标准纳入患者，并使用《现状检查》和《个人及精神病史记录表》进行年度评估。3年后，64例患者得到随访。其中，38例患者有一次或多次复发。复发组与未复发组的比较显示，某些变量与复发显著相关。其中一些变量包括随访的规律性、情感症状的存在、自我忽视以及缺乏社会交往。本文讨论了识别这些因素对于预防精神分裂症复发的重要性。
