Tarrier N, Barrowclough C, Bamrah J S
Department of Psychology, University of Sydney, Australia.
Soc Psychiatry Psychiatr Epidemiol. 1991 Aug;26(4):157-61. doi: 10.1007/BF00795207.
Fifty-six patients who were hospitalised for a schizophrenic episode were followed up for nine months after discharge. The Psychiatric Assessment Scale (PAS, Krawiecka et al., 1977) was administered at monthly intervals during this period. Twenty-three patients relapsed of which data were available for sixteen. In these sixteen patients who relapsed comparisons were made of the PAS symptoms between the month prior to relapse and the month preceding this. Sixteen patients who did not relapse were randomly matched with the relapsing patients and an index point comparable in time to relapse onset in the matched relapsed patient was identified. Comparisons were made on the PAS symptoms using a repeated measures ANOVA to compare relapsers and non relapsers on the month prior to relapse and the month which preceded this. Discriminant function analysis was used to predict relapse by analysis of those PAS symptoms which showed an increase in the month before relapse. This suggested that the measures of depression and hallucinations significantly increased in the month prior to relapse compared to the preceding month in relapsers but not non-relapsers. The results of this study closely agree with previous published results even though there were some differences between studies in the patient samples.
56名因精神分裂症发作住院的患者在出院后接受了9个月的随访。在此期间，每月使用《精神病评估量表》（PAS，克拉维茨卡等人，1977年）进行评估。23名患者复发，其中16名患者的数据可用。对这16名复发患者复发前一个月与此前一个月的PAS症状进行了比较。16名未复发的患者与复发患者进行随机匹配，并确定了与匹配的复发患者复发开始时间相当的一个时间点。使用重复测量方差分析对复发患者和未复发患者在复发前一个月和此前一个月的PAS症状进行比较。判别函数分析通过分析那些在复发前一个月有所增加的PAS症状来预测复发。这表明，与前一个月相比，复发患者在复发前一个月的抑郁和幻觉指标显著增加，而未复发患者则没有。本研究结果与之前发表的结果非常一致，尽管不同研究的患者样本存在一些差异。
