Rossi Tommaso, Querzoli Giorgio, Angelini Giampiero, Malvasi Carlo, Iossa Mario, Placentino Luca, Ripandelli Guido
*Eye Hospital of Rome, University of Cagliari, Cagliari, Italy, FAculty of Engineering, DICAT Department, Bietti Foundation IRCCS, Rome, Italy, Optikon 2000 Inc, Rome, Italy; †University of Cagliari, DICAAR; ‡Optikon 2000 Inc; and §Fondazione G.B. Bietti, IRCCS.
Retina. 2014 Sep;34(9):1896-904. doi: 10.1097/IAE.0000000000000143.
To assess the efficacy of novel vitreous cutter blades compared with the regular guillotine by means of particle image velocimetry. Tested blades included a regular blade (RB) and newer designs where a circular (hole blade [HB]) or a slit aperture (slit blade [SB]) had been opened proximal to the cutting edge.
Twenty-three-gauge probes were immersed in BSS or egg albumen, and high-speed video (1,000 frames per second) was recorded. Duty cycle, flow rate, and acceleration generated by Venturi and peristaltic pumps were measured under cutter settings simulating "low-speed" vitrectomy (1600 cuts per minute, 200 mmHg vacuum) and "high speed" vitrectomy (3000 cuts per minute, 300 mmHg vacuum).
The SB and HB had a significantly more favorable duty cycle than that of the RB (P < 0.01) and higher BSS flow rate regardless of the aspiration. The SB flow rate in albumen was significantly higher than that of the HB and RB only over 1,000 cuts per minute using a peristaltic pump and at any cut rate with Venturi pump (P < 0.001). The SB also yielded the lowest fluid acceleration than both the HB and SB (P < 0.001 in all cases).
The HB and SB proved to be significantly more efficient than the RB, with better duty cycle and higher flow rate. The SB generated significantly less fluid acceleration than any other tested blade, regardless of the fluid viscosity and pump technology. The SB design is significantly more efficient and possibly safer than both HB and RB.
通过粒子图像测速技术评估新型玻璃体切割器刀片与常规断头台式刀片的效能。测试的刀片包括常规刀片（RB）以及在切割边缘近端开有圆形（孔状刀片[HB]）或狭缝孔径（狭缝刀片[SB]）的新型设计刀片。
将23号探针浸入平衡盐溶液（BSS）或蛋清中，并记录高速视频（每秒1000帧）。在模拟“低速”玻璃体切除术（每分钟1600次切割，200 mmHg真空度）和“高速”玻璃体切除术（每分钟3000次切割，300 mmHg真空度）的切割器设置下，测量文丘里泵和蠕动泵产生的占空比、流速及加速度。
SB和HB的占空比明显优于RB（P < 0.01），且无论抽吸情况如何，其BSS流速更高。仅在使用蠕动泵每分钟超过1000次切割时以及使用文丘里泵在任何切割速率下，蛋清中的SB流速显著高于HB和RB（P < 0.001）。SB产生的流体加速度也低于HB和RB（在所有情况下P < 0.001）。
HB和SB被证明比RB效率显著更高，具有更好的占空比和更高的流速。无论流体粘度和泵技术如何，SB产生的流体加速度明显低于任何其他测试刀片。SB设计比HB和RB效率显著更高且可能更安全。
