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支原体感染后急性小纤维神经病:吉兰-巴雷综合征的一种罕见变异型

Acute small fiber neuropathy following Mycoplasma infection: a rare variant of Guillain-Barré syndrome.

作者信息

Makonahalli Rohitha, Seneviratne Janaka, Seneviratne Udaya

机构信息

*Department of Neuroscience, Monash Medical Centre, Clayton, Victoria, Australia; and †Monash University, Melbourne, Victoria, Australia.

出版信息

J Clin Neuromuscul Dis. 2014 Jun;15(4):147-51. doi: 10.1097/CND.0000000000000031.

Abstract

Guillain-Barré syndrome (GBS) is a well-described condition involving the peripheral nervous system. The most well-known form of this disease is acute inflammatory demyelinating polyradiculoneuropathy. Among the different variants of GBS described in the literature, the sensory variant is scantily recognized. There has been a recent attempt to classify the sensory variants of the GBS and bring more objectivity to this diagnostic paradigm. We report a rare sensory variant of GBS presenting with isolated small nerve fiber involvement peripherally in the limbs and associated facial nerve palsy in a patient who had clinical and serological evidence of a preceding Mycoplasma pneumoniae infection. The symptoms resolved gradually with intravenous immunoglobulin therapy. This case adds to the growing literature of the rare form of acute small fiber neuropathy and GBS variants.

摘要

吉兰-巴雷综合征(GBS)是一种已被充分描述的累及周围神经系统的疾病。该疾病最广为人知的形式是急性炎症性脱髓鞘性多发性神经根神经病。在文献中描述的GBS的不同变体中,感觉变体很少被认识到。最近有人尝试对GBS的感觉变体进行分类,并使这种诊断模式更具客观性。我们报告了一例罕见的GBS感觉变体,该患者四肢周围孤立的小神经纤维受累,并伴有面神经麻痹,患者有先前肺炎支原体感染的临床和血清学证据。症状通过静脉注射免疫球蛋白治疗逐渐缓解。该病例增加了关于急性小纤维神经病和GBS变体这种罕见形式的不断增长的文献。

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