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一所监狱中爆发的周围神经病变

An Outbreak of Peripheral Neuropathy in a Prison.

作者信息

Tiamkao Somsak, Boonsong Anuwat, Saepeung Kamol, Kasemsap Narongrit, Apiwattanakul Metha, Suanprasert Narupat, Hemachudha Thiravat, Pithak Prakai, Juntee Kittiphit, Waisaen Chamnan, Madha Supat, Buathong Rome, Sawanyawisuth Kittisak

机构信息

Division of Neurology, Department of Medicine, Faculty of Medicine, and Integrated Epilepsy Research Group, Khon Kaen University, Khon Kaen, Thailand.

Bueng Kan Hospital, Bueng Kan, Thailand.

出版信息

Case Rep Neurol. 2019 Feb 26;11(1):53-60. doi: 10.1159/000496536. eCollection 2019 Jan-Apr.

Abstract

Prisoners are at risk for both physical and psychological diseases. Here, we report an outbreak of peripheral neuropathy in a prison in northeast Thailand. Between July and December 2014, there were 88 male prisoners at Bueng Kan Provincial Prison in Bueng Kan, Thailand suffering from peripheral neuropathy out of a total of 1,464 prisoners (6.01%). The common age range was 20-39 years (58 patients; 65.91%). The three most common features were hyporeflexia/areflexia of the lower extremities (36 patients; 83.72%). On laboratory vitamin B1 deficiency was detected in 4/5 patients, positive rhinovirus polymerase chain reaction in 3/4 patients, positive IgM in 1/12 patients, and positive urinary arsenic in 4/7 patients. A dT vaccination was given on October 14 during the outbreak. This was a large outbreak of peripheral neuropathy in male prisoners. There are several possible causes of this outbreak including vitamin B1 deficiency, dT vaccination, arsenic toxicity, rhinovirus, and Mycoplasma infection.

摘要

囚犯面临身体和心理疾病的风险。在此,我们报告泰国东北部一所监狱爆发的周围神经病变疫情。2014年7月至12月期间,泰国廊开府廊开府省级监狱的1464名囚犯中有88名男性囚犯患有周围神经病变(占6.01%)。常见年龄范围为20 - 39岁(58例患者;占65.91%)。三个最常见的特征是下肢反射减退/无反射(36例患者;占83.72%)。在实验室检查中,5例患者中有4例检测出维生素B1缺乏,4例患者中有3例鼻病毒聚合酶链反应呈阳性,12例患者中有1例IgM呈阳性,7例患者中有4例尿砷呈阳性。在疫情期间于10月14日进行了白喉破伤风疫苗接种。这是男性囚犯中一次大规模的周围神经病变疫情爆发。此次疫情爆发有几种可能的原因,包括维生素B1缺乏、白喉破伤风疫苗接种、砷中毒、鼻病毒和支原体感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c92d/6739697/430a0d95e680/crn-0011-0053-g01.jpg

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