Khan J A, Grove A S, Joseph M P, Goodman M
Kansas University Medical Center, Department of Ophthalmology, Kansas City 66103.
Ophthalmic Plast Reconstr Surg. 1989;5(4):227-34. doi: 10.1097/00002341-198912000-00001.
Twenty cases of adnexal sebaceous carcinoma managed by contemporary methods, including monitoring of surgical margins, were reviewed. Eight of 20 patients were taking diuretic medications. The initial clinical diagnosis was incorrect in all cases, and 50% of cases were misdiagnosed by the pathologist interpreting the initial biopsy. The canaliculus was identified in 7 cases, and was involved by tumor in 3 cases. Tumor was identified in the lacrimal sac and inferior turbinate in an additional case. Thus, tumor spread into the lacrimal excretory system was documented by histologic findings in 4 cases.
回顾了采用当代方法（包括监测手术切缘）治疗的20例附件皮脂腺癌病例。20例患者中有8例正在服用利尿药物。所有病例的初始临床诊断均不正确，50%的病例被解读初始活检的病理学家误诊。7例中发现了泪小管，其中3例有肿瘤累及。另外1例在泪囊和下鼻甲发现肿瘤。因此，组织学检查结果证实4例肿瘤扩散至泪排泄系统。
