Federal Budget Scientific Institution, Federal Scientific Center for Medical and Preventive Health Risk Management Technologies, Perm 614000, Russia.
Comput Math Methods Med. 2014;2014:492489. doi: 10.1155/2014/492489. Epub 2014 Apr 27.
The concept of the triad regulatory metasystem, which includes the neuroendocrine and immune regulation systems, is currently generally accepted. Changes occurring in each of the regulatory systems in response to the impact of technogenic chemical factors are also well known. This paper presents mathematical models of the immune and neuroendocrine system functioning, using the interaction between these systems in response to bacterial invasion as an example, and changes in their performance under exposure to chemical factors, taking into account the stage of functional disorders in a producing organ, using the performance of the bone marrow as an example.
目前普遍接受的是包括神经内分泌和免疫系统调节在内的三联调节元概念。众所周知，每个调节系统在受到人为化学因素影响时都会发生变化。本文提出了免疫系统和神经内分泌系统功能的数学模型，以这些系统在受到细菌入侵时的相互作用为例，并考虑到产生器官功能障碍的阶段，以骨髓功能为例，研究了在接触化学因素时它们的性能变化。
