集落刺激因子（CSFs）对粒细胞吞噬功能的体内效应。
The in vivo effect of colony stimulating factors (CSFs) on phagocytic functions of granulocytes.
作者信息
Szmitkowski M, Cimaszewska M, Kondracka E, Wysocka J
机构信息
Department of Biochemical Diagnostics, Institute of Laboratory Diagnostics, Medical Academy, Białystok.
出版信息
Arch Immunol Ther Exp (Warsz). 1989;37(5-6):593-600.
The effect of commercially available colony stimulating factors and mouse post-endotoxin serum on bactericidal activity and phagocytosis of bacteria by blood neutrophils was tested on mice in vivo after intraperitoneal injection. It was found that tested substances are able to induce phagocytosis and bactericidal activity of blood granulocytes. The similar patterns of these actions during 48 hours were observed for mouse IL-3 and human GM-CSF and for GCT-CM and post-endotoxin serum.
在小鼠体内腹腔注射后，测试了市售集落刺激因子和小鼠内毒素后血清对血液中性粒细胞杀菌活性和细菌吞噬作用的影响。发现受试物质能够诱导血液粒细胞的吞噬作用和杀菌活性。在48小时内，观察到小鼠IL-3和人GM-CSF以及GCT-CM和内毒素后血清在这些作用上具有相似的模式。
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