Thiele Robert H, Raphael Jacob
University of Virginia Health System, Charlottesville, VA, USA.
University of Virginia Health System, Charlottesville, VA, USA
Semin Cardiothorac Vasc Anesth. 2014 Jun;18(2):177-89. doi: 10.1177/1089253214534782.
Coagulopathy after cardiac surgery with cardiopulmonary bypass is a serious complication that may result in massive bleeding requiring transfusion of significant amounts of blood products, plasma, and platelets. In addition to increased patient morbidity and mortality it is associated with longer hospital stay and increased resource utilization. The current review discusses aspects in cardiopulmonary bypass-induced coagulopathy with emphasis on point-of-care testing and individualized "goal-directed" therapy in patients who develop excessive bleeding after cardiac surgery.
体外循环心脏手术后的凝血功能障碍是一种严重并发症，可能导致大量出血，需要输注大量血液制品、血浆和血小板。除了增加患者的发病率和死亡率外，它还与更长的住院时间和更高的资源利用率相关。本综述讨论了体外循环引起的凝血功能障碍的相关方面，重点是对心脏手术后发生过度出血的患者进行床旁检测和个体化的“目标导向”治疗。
