结直肠癌肺转移瘤切除术：多少个结节，需进行几次手术？
Pulmonary metastasectomy for colorectal cancer: how many nodules, how many times?
作者信息
Kim Hong Kwan, Cho Jong Ho, Lee Ho Yun, Lee Jeeyun, Kim Jhingook
机构信息
Hong Kwan Kim, Jong Ho Cho, Jhingook Kim, Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, South Korea.
出版信息
World J Gastroenterol. 2014 May 28;20(20):6133-45. doi: 10.3748/wjg.v20.i20.6133.
Abstract
Colorectal cancer (CRC) is one of the most common cancers worldwide, with 5%-15% of CRC patients eventually developing lung metastasis (LM). Despite doubts about the role of locoregional therapy in the management of systemic disease, many surgeons have performed pulmonary metastasectomy (PM) for CRC in properly selected patients. However, the use of pulmonary metastasectomy remains controversial due to the lack of randomized controlled studies. This article reviews the results of surgical treatment of pulmonary metastases for CRC, focusing on (1) current treatment guidelines and surgical techniques of PM in patients with LM from CRC; (2) outcomes of PM and its prognostic factors; and (3) controversial issues in PM, focusing on repeated metastasectomy, bilateral multiple metastases, and combined liver and lung metastasectomy.
摘要
结直肠癌（CRC）是全球最常见的癌症之一，5%-15%的CRC患者最终会发生肺转移（LM）。尽管对于局部区域治疗在全身性疾病管理中的作用存在疑问，但许多外科医生已对经过适当选择的CRC患者实施了肺转移瘤切除术（PM）。然而，由于缺乏随机对照研究，肺转移瘤切除术的应用仍存在争议。本文回顾了CRC肺转移的外科治疗结果，重点关注：（1）CRC发生LM患者的PM当前治疗指南和手术技术；（2）PM的结果及其预后因素；（3）PM中的争议问题，重点关注重复转移瘤切除术、双侧多发转移以及肝肺联合转移瘤切除术。
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