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慢性阻塞性肺疾病的自我管理和运动作为肺康复治疗:一项随机对照试验。

Chronic disease self-management and exercise in COPD as pulmonary rehabilitation: a randomized controlled trial.

机构信息

Centre of Research Excellence for Chronic Respiratory Disease and Lung Aging, School of Medicine, University of Tasmania, Hobart, TAS, Australia.

Faculty of Education, University of Tasmania, Hobart, TAS, Australia.

出版信息

Int J Chron Obstruct Pulmon Dis. 2014 May 19;9:513-23. doi: 10.2147/COPD.S58478. eCollection 2014.

Abstract

PURPOSE

Both exercise and self-management are advocated in pulmonary rehabilitation for people with chronic obstructive pulmonary disease (COPD). The widely used 6-week, group-based Chronic Disease Self-Management Program (CDSMP) increases self-reported exercise, despite supervised exercise not being a program component. This has been little explored in COPD. Whether adding supervised exercise to the CDSMP would add benefit is unknown. We investigated the CDSMP in COPD, with and without a formal supervised exercise component, to address this question.

PATIENTS AND METHODS

Adult outpatients with COPD were randomized to the CDSMP with or without one hour of weekly supervised exercise over 6 weeks. The primary outcome measure was 6-minute walk test distance (6MWD). Secondary outcomes included self-reported exercise, exercise stage of change, exercise self-efficacy, breathlessness, quality of life, and self-management behaviors. Within- and between-group differences were analyzed on an intention-to-treat basis.

RESULTS

Of 84 subjects recruited, 15 withdrew. 6MWD increased similarly in both groups: CDSMP-plus-exercise (intervention group) by 18.6±46.2 m; CDSMP-alone (control group) by 20.0±46.2 m. There was no significant difference for any secondary outcome.

CONCLUSION

The CDSMP produced à small statistically significant increase in 6MWD. The addition of a single supervised exercise session did not further increase exercise capacity. Our findings confirm the efficacy of a behaviorally based intervention in COPD, but this would seem to be less than expected from conventional exercise-based pulmonary rehabilitation, raising the question of how, if at all, the small gains observed in this study may be augmented.

摘要

目的

运动和自我管理都被提倡用于慢性阻塞性肺疾病(COPD)患者的肺康复。广泛使用的 6 周、基于小组的慢性疾病自我管理计划(CDSMP)增加了自我报告的运动,尽管监督运动不是该计划的组成部分。这在 COPD 中很少被探讨。在 CDSMP 中加入监督运动是否会带来额外的益处尚不清楚。我们调查了 COPD 患者的 CDSMP,包括有无一个小时的每周监督运动,共 6 周。主要观察指标是 6 分钟步行测试距离(6MWD)。次要观察指标包括自我报告的运动、运动阶段的变化、运动自我效能、呼吸困难、生活质量和自我管理行为。基于意向治疗进行了组内和组间差异分析。

方法

成年 COPD 门诊患者被随机分配到 CDSMP 加或不加每周一小时的监督运动,共 6 周。主要观察指标是 6 分钟步行测试距离(6MWD)。次要观察指标包括自我报告的运动、运动阶段的变化、运动自我效能、呼吸困难、生活质量和自我管理行为。基于意向治疗进行了组内和组间差异分析。

结果

在招募的 84 名患者中,有 15 名退出。两组的 6MWD 增加相似:CDSMP 加运动(干预组)增加了 18.6±46.2m;CDSMP 单独组(对照组)增加了 20.0±46.2m。任何次要结果都没有显著差异。

结论

CDSMP 使 6MWD 有一个小的统计学显著增加。增加一次监督运动并没有进一步增加运动能力。我们的研究结果证实了基于行为的干预在 COPD 中的有效性,但这似乎低于传统基于运动的肺康复的预期,这就提出了一个问题,即无论如何,在这项研究中观察到的微小收益如何增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a613/4037329/0b5da4ad6836/copd-9-513Fig1.jpg

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