Terauchi Gaku, Matsumoto Celso Soiti, Shinoda Kei, Matsumoto Harue, Imamura Yutaka, Watanabe Emiko, Kondo Takaaki, Mizota Atsushi
Department of Ophthalmology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-0003, Japan.
Department of Ophthalmology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-0003, Japan ; Matsumoto Eye Clinic, Tokushima 771-1705, Japan.
Case Rep Med. 2014;2014:786578. doi: 10.1155/2014/786578. Epub 2014 Apr 30.
Background. To report the outcome of pars plana vitrectomy (PPV) combined with intraoperative endolaser focal photocoagulation (PC) on eyes with idiopathic macular telangiectasis (MacTel) type 1. Methods. This was a retrospective study of two female patients with MacTel type 1 who were resistant to focal photocoagulation, sub-Tenon triamcinolone injection, and/or antiangiogenic drugs. The best-corrected visual acuity (BCVA) was determined, and fluorescein angiography (FA) and spectral domain optical coherence tomography (SD-OCT) were performed before and after surgery for up to 19 months. Results. After surgery, the BCVA gradually improved from 20/100 to 20/20 at 19 months in Case 1 and from 20/50 to 20/13 at 13 months in Case 2. Fluorescein angiography (FA) showed leakage at the late phase, and OCT showed that the cystoid macular edema was resolved and the fovea was considerably thinner postoperatively. Conclusion. Patients with MacTel type 1 who are refractory to the other types of treatments can benefit from PPV combined with intraoperative endolaser focal PC with functional and morphological improvements.
背景。报告玻璃体切除术（PPV）联合术中激光聚焦光凝（PC）治疗1型特发性黄斑毛细血管扩张症（MacTel）患者的疗效。方法。这是一项回顾性研究，研究对象为两名对局部光凝、球后注射曲安奈德和/或抗血管生成药物治疗无效的1型MacTel女性患者。测定最佳矫正视力（BCVA），并在手术前后进行长达19个月的荧光素血管造影（FA）和光谱域光学相干断层扫描（SD-OCT）。结果。术后，病例1的BCVA在19个月时从20/100逐渐提高到20/20，病例2的BCVA在13个月时从20/50提高到20/13。荧光素血管造影（FA）显示晚期渗漏，OCT显示术后黄斑囊样水肿消退，黄斑中心凹明显变薄。结论。对其他类型治疗无效的1型MacTel患者可从PPV联合术中激光聚焦PC中获益，功能和形态均有改善。
