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腹腔镜手术治疗深部浸润型子宫内膜异位症的长期疗效:900例单中心经验

Long-term outcome after laparoscopic bowel resections for deep infiltrating endometriosis: a single-center experience after 900 cases.

作者信息

Ruffo Giacomo, Scopelliti Filippo, Manzoni Alberto, Sartori Alberto, Rossini Roberto, Ceccaroni Marcello, Minelli Luca, Crippa Stefano, Partelli Stefano, Falconi Massimo

机构信息

Department of General Surgery, Sacro Cuore Don Calabria General Hospital, Via Don A. Sempreboni 5, 37024 Negrar, Italy.

Department of Obstetrics and Gynecology, Sacro Cuore Don Calabria General Hospital, Via Don A. Sempreboni 5, 37024 Negrar, Italy.

出版信息

Biomed Res Int. 2014;2014:463058. doi: 10.1155/2014/463058. Epub 2014 Apr 29.

Abstract

BACKGROUND

Laparoscopic bowel resections for endometriosis are safe and effective but only short-term follow-up has been evaluated. In the present study long-term outcome in terms of intestinal and urinary function, fertility, chronic pain, and recurrence was assessed.

MATERIALS AND METHODS

From January 2002 to December 2010 nine hundred patients underwent laparoscopic bowel resection for endometriosis, and on 774 (86%) a questionnaire was administered. Patients were divided into 3 groups on the strength of the operation date. Postoperative diarrhea, constipation, rectal bleeding, tenesmus, dyschezia, dysuria, dyspareunia, fertility, and recurrence of disease were assessed.

RESULTS

The median follow-up was 54 months (range 1-120). All the evaluated symptoms significantly improved over time, with P = 0.0001 for dyspareunia, constipation, and pelvic pain and P = 0.004 for diarrhea. Nonsignificant improvement was reported for dysuria and rectal bleeding (with P = 0.452 and P = 0.097, resp.).

CONCLUSIONS

The present results confirm that bowel resections for endometriosis are correlated with an acceptable complication rate even at long-term follow-up and that symptoms significantly improve over time, except for rectal bleeding and dysuria, the latter associated with a neurological damage.

摘要

背景

腹腔镜下子宫内膜异位症肠道切除术安全有效,但仅进行了短期随访评估。在本研究中,评估了肠道和泌尿系统功能、生育能力、慢性疼痛及复发方面的长期结果。

材料与方法

2002年1月至2010年12月,900例患者接受了腹腔镜下子宫内膜异位症肠道切除术,其中774例(86%)接受了问卷调查。根据手术日期将患者分为3组。评估术后腹泻、便秘、直肠出血、里急后重、排便困难、排尿困难、性交困难、生育能力及疾病复发情况。

结果

中位随访时间为54个月(范围1 - 120个月)。所有评估症状随时间均有显著改善,性交困难、便秘及盆腔疼痛P = 0.0001,腹泻P = 0.004。排尿困难和直肠出血改善不显著(分别为P = 0.452和P = 0.097)。

结论

目前结果证实,即使在长期随访中,子宫内膜异位症肠道切除术的并发症发生率仍可接受,且除直肠出血和排尿困难(后者与神经损伤有关)外,症状随时间显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93bd/4022010/7bf160ee9a23/BMRI2014-463058.001.jpg

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