Saitoh H, Shinohara Y, Fujita H, Aoki Y, Takagi S
Department of Neurology, School of Medicine, Tokai University, Kanagawa, Japan.
Tokai J Exp Clin Med. 1989 Sep;14(4):357-60.
In a patient with carmofur-induced leukoencephalopathy with a fairly good prognosis, serial MR images demonstrated reversible abnormal signal intensity areas located in the cerebral white matter surrounding the lateral ventricles. These findings suggested that the edematous change together with demyelination of the white matter is important in the pathogenesis underlying carmofur-induced leukoencephalopathy.
在一名预后相当良好的卡莫氟诱导性白质脑病患者中,系列磁共振成像显示侧脑室周围脑白质存在可逆性异常信号强度区域。这些发现表明,白质的水肿改变以及脱髓鞘在卡莫氟诱导性白质脑病的发病机制中具有重要作用。