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对阿司匹林过敏的患者经皮冠状动脉介入治疗后的单药抗血小板治疗

Single antiplatelet therapy after percutaneous coronary intervention in patients allergic to aspirin.

作者信息

Agarwal Sanjeev Kumar

机构信息

Cardiology, Rashid Hospital, Dubai, UAE.

出版信息

Cardiovasc Revasc Med. 2014 Jul-Aug;15(5):308-10. doi: 10.1016/j.carrev.2014.04.005. Epub 2014 Apr 30.

DOI:10.1016/j.carrev.2014.04.005
PMID:24880912
Abstract

Dual antiplatelet therapy including aspirin and a P2Y12 ADP receptor antagonist is given after percutaneous coronary intervention to avoid catastrophic complication of stent thrombosis. Dual antiplatelet therapy is associated with increased bleeding risk and may not be tolerated by many patients. This article presents the patients, which had to be given single antiplatelet therapy after percutaneous coronary intervention and discusses the possible factors responsible for the success of single antiplatelet therapy strategy in these patients, in the current era of newer antiplatelet agents and coronary stents.

摘要

经皮冠状动脉介入治疗后给予包括阿司匹林和P2Y12 ADP受体拮抗剂在内的双重抗血小板治疗,以避免支架血栓形成这一灾难性并发症。双重抗血小板治疗会增加出血风险,且许多患者可能无法耐受。本文介绍了经皮冠状动脉介入治疗后必须接受单一抗血小板治疗的患者,并讨论了在当前使用新型抗血小板药物和冠状动脉支架的时代,这些患者单一抗血小板治疗策略成功的可能因素。

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引用本文的文献

1
The efficacy and safety of cilostazol as an alternative to aspirin in Chinese patients with aspirin intolerance after coronary stent implantation: a combined clinical study and computational system pharmacology analysis.西洛他唑作为冠状动脉支架植入术后阿司匹林不耐受的中国患者替代阿司匹林的疗效和安全性:一项联合临床研究和计算系统药理学分析。
Acta Pharmacol Sin. 2018 Feb;39(2):205-212. doi: 10.1038/aps.2017.85. Epub 2017 Sep 21.