通过铜介导的氧化C-H官能化反应简洁合成高度取代的咪唑。
A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization.
作者信息
Pandya Amit N, Agrawal Devendra K
机构信息
Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, NE 68178, USA.
Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, NE 68178, USA ; Center for Clinical and Translational Science, Creighton University School of Medicine, Omaha, NE 68178, USA.
出版信息
Tetrahedron Lett. 2014 Mar 5;55(10):1835-1838. doi: 10.1016/j.tetlet.2014.01.136.
Abstract
We herein report a simple and concise route for the synthesis of highly substituted imidazole derivatives via copper-mediated oxidative C-H functionalization in good to high yields. The advantage of the reaction lies in its mild reaction conditions and readily available starting materials.
摘要
我们在此报道了一条通过铜介导的氧化C-H官能化反应以良好至高产率合成高度取代咪唑衍生物的简单而简洁的路线。该反应的优点在于其温和的反应条件和易于获得的起始原料。
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