Bodhade Ashish S, Dive Alka M
Department of Oral and Maxillofacial Pathology, VSPM'S Dental College and Research Center, Digdoh Hills, Hingana Road, Nagpur, Maharashtra, India.
Eur J Dent. 2013 Apr;7(2):246-250. doi: 10.4103/1305-7456.110198.
The word chemoprevention includes prevention of initiation, promotion, and progression of carcinogenesis to cancer. This article is an attempt to review the dietary chemopreventive agents and their mode of action in chemoprevention of oral premalignant lesions and oral cancer using a systematic approach. Selected chemoprevention trials are discussed with a focus on strategies of trial design and clinical outcome. Future in the field of chemoprevention will be more promising than the recently available therapeutic alternatives.
化学预防一词包括预防致癌作用起始、促进以及进展为癌症。本文旨在采用系统方法综述膳食化学预防剂及其在口腔癌前病变和口腔癌化学预防中的作用模式。文中讨论了选定的化学预防试验,重点关注试验设计策略和临床结果。化学预防领域的未来将比近期可用的治疗选择更具前景。