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本文引用的文献

1
Systematic comprehensive geriatric assessment in elderly patients on chronic dialysis: a cross-sectional comparative and feasibility study.慢性透析老年患者的系统全面老年评估:一项横断面比较和可行性研究。
BMC Nephrol. 2012 May 30;13:30. doi: 10.1186/1471-2369-13-30.
2
Factors influencing patient choice of dialysis versus conservative care to treat end-stage kidney disease.影响终末期肾病患者选择透析与保守治疗的因素。
CMAJ. 2012 Mar 20;184(5):E277-83. doi: 10.1503/cmaj.111355. Epub 2012 Feb 6.
3
Clinical practices and outcomes in elderly hemodialysis patients: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS).老年血液透析患者的临床实践和结局:来自透析结局和实践模式研究(DOPPS)的结果。
Clin J Am Soc Nephrol. 2011 Jul;6(7):1651-62. doi: 10.2215/CJN.03530410.
4
Survival of elderly patients with stage 5 CKD: comparison of conservative management and renal replacement therapy.老年 5 期 CKD 患者的生存:保守治疗与肾脏替代治疗的比较。
Nephrol Dial Transplant. 2011 May;26(5):1608-14. doi: 10.1093/ndt/gfq630. Epub 2010 Nov 22.
5
Maximum conservative management for patients with chronic kidney disease stage 5.对5期慢性肾脏病患者的最大保守治疗
Hemodial Int. 2010 Oct;14 Suppl 1:S32-7. doi: 10.1111/j.1542-4758.2010.00488.x.
6
End-of-life care preferences and needs: perceptions of patients with chronic kidney disease.终末期关怀的偏好和需求:慢性肾脏病患者的看法。
Clin J Am Soc Nephrol. 2010 Feb;5(2):195-204. doi: 10.2215/CJN.05960809. Epub 2010 Jan 14.
7
Palliative care in the treatment of advanced heart failure.晚期心力衰竭治疗中的姑息治疗。
Circulation. 2009 Dec 22;120(25):2597-606. doi: 10.1161/CIRCULATIONAHA.109.869123.
8
Functional status of elderly adults before and after initiation of dialysis.老年成年人开始透析前后的功能状态。
N Engl J Med. 2009 Oct 15;361(16):1539-47. doi: 10.1056/NEJMoa0904655.
9
A clinical score to predict 6-month prognosis in elderly patients starting dialysis for end-stage renal disease.一种用于预测开始接受透析治疗的老年终末期肾病患者6个月预后的临床评分。
Nephrol Dial Transplant. 2009 May;24(5):1553-61. doi: 10.1093/ndt/gfn698. Epub 2008 Dec 18.
10
Understanding symptoms in patients with advanced chronic kidney disease managed without dialysis: use of a short patient-completed assessment tool.了解未接受透析治疗的晚期慢性肾病患者的症状:使用一种简短的患者自评评估工具。
Nephron Clin Pract. 2009;111(1):c74-80. doi: 10.1159/000183177. Epub 2008 Dec 16.

姑息性透析:视角的转变。

Palliative dialysis: a change of perspective.

作者信息

Romano Thiago Gomes, Palomba Henrique

机构信息

Nephrology Department, ABC Medical School, Brazil ; Sirio Libanes Hospital, Intensive Care Unit, Brazil ; Sancta Maggiori Hospital, Brazil.

Sancta Maggiori Hospital, Brazil ; Albert Einstein Hospital, Intensive Care Unit, Brazil.

出版信息

J Clin Med Res. 2014 Aug;6(4):234-8. doi: 10.14740/jocmr1773w. Epub 2014 May 22.

DOI:10.14740/jocmr1773w
PMID:24883146
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4039092/
Abstract

The aging phenomenon of dialysis patients is a worldwide reality, observed in developed and developing countries. Those patients have high incidence of chronic conditions along with high mortality rates and for some of them a decline in functional status within the first 12 months of dialysis therapy. Nevertheless, the elderly dialysis patients represent a very heterogeneous group where prognostic tools may help the decision-making process together with family members, medical staff and the patients. Despite the fact that there are many validated prognostic tools in elderly population, no score has the aim to guide the decision to withhold or withdrawn the dialysis procedure; therefore, in many cases, a time-limited trial is supported. After the failure of improvement in life quality and certitude of the poor prognosis, the withdrawing from renal replacement therapy can be done. Medical literature, from developed countries, brings robust evidence that the process of withdrawing the dialysis procedure, after a fail in the so-called "time-limited trial", along with good quality palliative care in this scenario is related to a good quality of death. We, on the other hand, believe that the withdrawing process in countries where hospice and good palliative care is not a reality may be associated with bad outcomes. Therefore, this review discusses a way to improve end-of-life symptoms in countries where palliative care facilities are not a reality, the so-called "palliative dialysis".

摘要

透析患者的老龄化现象是一个全球普遍存在的现实,在发达国家和发展中国家均有观察到。这些患者慢性病发病率高,死亡率也高,其中一些患者在透析治疗的头12个月内功能状态就会下降。然而,老年透析患者是一个非常 heterogeneous 的群体,预后工具可能有助于家庭成员、医务人员和患者共同做出决策。尽管在老年人群中有许多经过验证的预后工具,但没有一个评分旨在指导决定停止或撤回透析程序;因此,在许多情况下,支持进行限时试验。在生活质量没有改善且预后不佳得到确认后,可以停止肾脏替代治疗。来自发达国家的医学文献提供了有力证据,即在所谓的“限时试验”失败后停止透析程序的过程,以及在这种情况下提供高质量的姑息治疗,与良好的死亡质量相关。另一方面,我们认为在临终关怀和良好的姑息治疗并不现实的国家,停止透析的过程可能会带来不良后果。因此,本综述讨论了在姑息治疗设施不现实的国家改善临终症状的方法,即所谓的“姑息性透析”。