Romano Thiago Gomes, Palomba Henrique
Nephrology Department, ABC Medical School, Brazil ; Sirio Libanes Hospital, Intensive Care Unit, Brazil ; Sancta Maggiori Hospital, Brazil.
Sancta Maggiori Hospital, Brazil ; Albert Einstein Hospital, Intensive Care Unit, Brazil.
J Clin Med Res. 2014 Aug;6(4):234-8. doi: 10.14740/jocmr1773w. Epub 2014 May 22.
The aging phenomenon of dialysis patients is a worldwide reality, observed in developed and developing countries. Those patients have high incidence of chronic conditions along with high mortality rates and for some of them a decline in functional status within the first 12 months of dialysis therapy. Nevertheless, the elderly dialysis patients represent a very heterogeneous group where prognostic tools may help the decision-making process together with family members, medical staff and the patients. Despite the fact that there are many validated prognostic tools in elderly population, no score has the aim to guide the decision to withhold or withdrawn the dialysis procedure; therefore, in many cases, a time-limited trial is supported. After the failure of improvement in life quality and certitude of the poor prognosis, the withdrawing from renal replacement therapy can be done. Medical literature, from developed countries, brings robust evidence that the process of withdrawing the dialysis procedure, after a fail in the so-called "time-limited trial", along with good quality palliative care in this scenario is related to a good quality of death. We, on the other hand, believe that the withdrawing process in countries where hospice and good palliative care is not a reality may be associated with bad outcomes. Therefore, this review discusses a way to improve end-of-life symptoms in countries where palliative care facilities are not a reality, the so-called "palliative dialysis".
透析患者的老龄化现象是一个全球普遍存在的现实,在发达国家和发展中国家均有观察到。这些患者慢性病发病率高,死亡率也高,其中一些患者在透析治疗的头12个月内功能状态就会下降。然而,老年透析患者是一个非常 heterogeneous 的群体,预后工具可能有助于家庭成员、医务人员和患者共同做出决策。尽管在老年人群中有许多经过验证的预后工具,但没有一个评分旨在指导决定停止或撤回透析程序;因此,在许多情况下,支持进行限时试验。在生活质量没有改善且预后不佳得到确认后,可以停止肾脏替代治疗。来自发达国家的医学文献提供了有力证据,即在所谓的“限时试验”失败后停止透析程序的过程,以及在这种情况下提供高质量的姑息治疗,与良好的死亡质量相关。另一方面,我们认为在临终关怀和良好的姑息治疗并不现实的国家,停止透析的过程可能会带来不良后果。因此,本综述讨论了在姑息治疗设施不现实的国家改善临终症状的方法,即所谓的“姑息性透析”。