Lee Si Won, Kim Moon Young, Kim Jung Eun, Chung Jin Hoon, Lee Hyun Jung, Yoon Ji Young
Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea.
Department of Obstetrics and Gynecology, Woosung Woman's Hospital, Ansan, Korea.
Obstet Gynecol Sci. 2014 May;57(3):181-6. doi: 10.5468/ogs.2014.57.3.181. Epub 2014 May 15.
This study reviewed clinical characteristics of fetal intra-abdominal umbilical vein (FIUV) varices that were detected during antenatal ultrasound examinations.
Between January 2006 and January 2012, 121 cases of FIUV varices were detected and 7 cases were lost to follow-up. We retrospectively reviewed the medical records of 114 patients and neonates.
From a total 96,553 ultrasound examinations in 43,995 pregnancies, 121 cases of FIUV varices were identified (2.8 per 1,000 pregnancies). Gestational age at diagnosis was 32.0 ± 2.9 weeks (range, 20.1-36.3 weeks), the mean diameter of the FIUV varix was 12.6 ± 2.1 mm (range, 8.0-21.0 mm) at initial diagnosis and the mean maximal diameter was 13.1 ± 2.3 mm (range, 8.0-21.0 mm) during follow-up. The most severe pregnancy complications included one case of intrauterine fetal death and another case of fetal hydrops. Associated fetal anomalies (n = 11, 9.6%) detected by ultrasonography included bilateral renal pelvis dilatation, ventriculomegaly, cryptorchidism, incomplete renal duplication and pulmonary sequestration. A total of 104 cases (91.2%) were delivered at term and 10 cases (8.8%) were preterm deliveries before 37 weeks of gestation.
FIUV varices that are not associated with fetal anomalies based on ultrasound examination during prenatal care have favorable pregnancy outcomes. Nevertheless, close fetal monitoring is recommended to decrease perinatal complications.
本研究回顾了产前超声检查时发现的胎儿腹腔内脐静脉（FIUV）曲张的临床特征。
2006年1月至2012年1月期间，共检测出121例FIUV曲张病例，其中7例失访。我们回顾性分析了114例患者及新生儿的病历。
在43,995例妊娠的96,553次超声检查中，共发现121例FIUV曲张（每1000例妊娠中有2.8例）。诊断时的孕周为32.0±2.9周（范围20.1 - 36.3周），初次诊断时FIUV曲张的平均直径为12.6±2.1毫米（范围8.0 - 21.0毫米），随访期间的平均最大直径为13.1±2.3毫米（范围8.0 - 21.0毫米）。最严重的妊娠并发症包括1例宫内胎儿死亡和1例胎儿水肿。超声检查发现的相关胎儿异常（n = 11，9.6%）包括双侧肾盂扩张、脑室扩大、隐睾、肾重复畸形不完全和肺隔离症。共有104例（91.2%）足月分娩，10例（8.8%）在妊娠37周前早产。
产前检查时超声检查未发现与胎儿异常相关的FIUV曲张，妊娠结局良好。然而，建议密切监测胎儿以减少围产期并发症。
