Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, The University of Texas Medical Branch, Galveston, TX 77573, USA.
Ultrasound Obstet Gynecol. 2009 Mar;33(3):282-6. doi: 10.1002/uog.6233.
Fetal intra-abdominal umbilical vein (FIUV) varix is a focal dilatation of the intra-abdominal portion of the umbilical vein, which has been reported to be associated with intrauterine death and other anomalies. Our aim was to examine our experience with this diagnosis at a single tertiary-care center and to correlate it with clinical outcome.
This was a retrospective case series study. Our ultrasound database was searched for all cases with a diagnosis of FIUV varix identified at our facility between 1997 and 2007. We reviewed all ultrasound examinations, maternal antenatal records, delivery records and newborns' medical records.
We identified 52 cases of FIUV among a population of approximately 68,000. Three cases of trisomy 21 were identified, all of which were accompanied by other anomalies. There was intrauterine death of one fetus with trisomy 21 at 35 weeks of gestation. We did not find an association between FIUV varix and other obstetric complications.
The outcome of pregnancies with FIUV varix is generally favorable. The finding of a FIUV varix should prompt the search for other anomalies, especially markers of aneuploidy.
胎儿腹腔内脐静脉（FIUV）静脉瘤是脐静脉腹腔内部分的局灶性扩张，已有报道与宫内死亡和其他异常有关。我们的目的是在一家三级保健中心检查我们对此诊断的经验，并将其与临床结果相关联。
这是一项回顾性病例系列研究。我们的超声数据库检索了 1997 年至 2007 年间在我们医院诊断为 FIUV 静脉瘤的所有病例。我们回顾了所有的超声检查、孕妇的产前记录、分娩记录和新生儿的病历。
我们在大约 68000 名孕妇中发现了 52 例 FIUV 病例。发现了 3 例 21 三体，均伴有其他异常。一例 21 三体胎儿在 35 周时宫内死亡。我们没有发现 FIUV 静脉瘤与其他产科并发症之间存在关联。
FIUV 静脉瘤妊娠的结局通常是有利的。发现 FIUV 静脉瘤应促使寻找其他异常，特别是非整倍体的标志物。
