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主动病例检测在疟疾消除计划中的重要性。

Importance of active case detection in a malaria elimination programme.

作者信息

Wickremasinghe Renu, Fernando Sumadhya Deepika, Thillekaratne Janani, Wijeyaratne Panduka Mahendra, Wickremasinghe Ananda Rajitha

机构信息

Department of Parasitology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila Nugegoda, Sri Lanka.

出版信息

Malar J. 2014 May 23;13:186. doi: 10.1186/1475-2875-13-186.

Abstract

BACKGROUND

With the aim of eliminating malaria from Sri Lanka by 2014, the Anti-Malaria Campaign of Sri Lanka (AMC) sought the support of Tropical and Environmental Disease and Health Associates Private Limited (TEDHA), a private sector organization. In 2009, TEDHA was assigned 43 government hospitals in the district of Mannar in the Northern Province and in districts of Trincomalee, Batticaloa and Ampara in the Eastern Province to carry out malaria surveillance to complement the surveillance activities of the AMC. Passive case detection (PCD), activated passive case detection (APCD) and active case detection (ACD) for malaria have been routinely carried out in Sri Lanka.

METHODS

The active case detection programme of TEDHA involves screening of populations irrespective of the presence of fever or any other signs or symptoms of malaria to detect infections and residual parasite carriers. ACD is done by TEDHA in a) high risk populations through mobile malaria clinics including armed forces personnel and b) pregnant females who visit antenatal clinics for asymptomatic malaria infections during the first trimester of pregnancy. Populations are selected in consultation with the Regional Malaria Officer of the AMC thus avoiding any overlap with the population screened by the government.

RESULTS

TEDHA screened 387,309 individuals in the four districts for malaria by ACD including high risk groups and pregnant women between January 2010 and December 2012. During this period seven individuals were diagnosed with Plasmodium vivax infections and one individual was detected with a mixed infection of P. vivax and Plasmodium falciparum. All eight cases were detected by ACD carried out by mobile malaria clinics among high risk groups in the Mannar district.

CONCLUSION

The progress made by Sri Lanka in the malaria elimination drive is largely due to increased surveillance and judicious use of control methods which has resulted in zero indigenous malaria cases being reported since October 2012. ACD played a major role in interrupting malaria transmission in the country.

摘要

背景

为了在2014年消除斯里兰卡的疟疾,斯里兰卡抗疟运动(AMC)寻求私营部门组织热带与环境疾病及健康协会私人有限公司(TEDHA)的支持。2009年,TEDHA被分配到北方省马纳尔区以及东部省亭可马里、拜蒂克洛和安帕拉区的43家政府医院,开展疟疾监测,以补充AMC的监测活动。在斯里兰卡,疟疾的被动病例检测(PCD)、激活被动病例检测(APCD)和主动病例检测(ACD)已常规开展。

方法

TEDHA的主动病例检测计划包括对人群进行筛查,无论其是否发烧或有任何其他疟疾体征或症状,以检测感染情况和残余寄生虫携带者。TEDHA通过以下方式进行主动病例检测:a)在包括武装部队人员在内的高风险人群中,通过流动疟疾诊所进行检测;b)对在妊娠头三个月到产前诊所就诊的无症状疟疾感染孕妇进行检测。在与AMC的区域疟疾官员协商后选择检测人群,从而避免与政府筛查的人群重叠。

结果

2010年1月至2012年12月期间,TEDHA通过主动病例检测在四个区对包括高风险群体和孕妇在内的387,309人进行了疟疾筛查。在此期间,7人被诊断为间日疟原虫感染,1人被检测为间日疟原虫和恶性疟原虫混合感染。所有8例病例均通过马纳尔区高风险群体中流动疟疾诊所开展的主动病例检测发现。

结论

斯里兰卡在疟疾消除运动中取得的进展很大程度上归功于监测的加强和控制方法的明智使用,自2012年10月以来已报告零本土疟疾病例。主动病例检测在该国疟疾传播阻断中发挥了重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2068/4042136/069ccfc82dd0/1475-2875-13-186-1.jpg

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