College of Veterinary Medicine, South China Agricultural University, No, 483 Wushan Road, Tianhe District, Guangzhou 510642, China.
Virol J. 2014 May 14;11:88. doi: 10.1186/1743-422X-11-88.
Currently, porcine circovirus type 2 (PCV2) is considered the major pathogen of porcine circovirus associated-diseases (PCVAD) that causes large economic losses for the swine industry in the world annually, including China. Since the first report of PCV2 in 1998, it has been drawing tremendous attention for the government, farming enterprises, farmers, and veterinary practitioners. Chinese researchers have conducted a number of molecular epidemiological work on PCV2 by molecular approaches in the past several years, which has resulted in the identification of novel PCV2 genotypes and PCV2-like agents as well as the description of new prevalence patterns. Since late 2009, commercial PCV2 vaccines, including the subunit vaccines and inactivated vaccines, have already been used in Chinese swine farms. The aim of this review is to update the insights into the prevalence and control of PCV2 in China, which would contribute to understanding the epidemiology, control measures and design of novel vaccines for PCV2.
目前,猪圆环病毒 2 型(PCV2)被认为是引起猪圆环病毒相关疾病(PCVAD)的主要病原体,每年给全球养猪业(包括中国)造成巨大的经济损失。自 1998 年首次报道 PCV2 以来,它一直受到政府、养殖企业、农民和兽医从业者的高度关注。过去几年,中国研究人员通过分子方法对 PCV2 进行了多项分子流行病学研究,鉴定了新型 PCV2 基因型和 PCV2 样病毒,并描述了新的流行模式。自 2009 年底以来,包括亚单位疫苗和灭活疫苗在内的商品化 PCV2 疫苗已在中国的猪场使用。本综述旨在更新对中国 PCV2 流行和控制的认识,这将有助于了解 PCV2 的流行病学、控制措施和新型疫苗的设计。