Matsuo Yoichi, Sato Mikinori, Shibata Takahiro, Morimoto Mamoru, Tsuboi Ken, Shamoto Tomoya, Hirokawa Takahisa, Sato Takafumi, Takahashi Hiroki, Takeyama Hiromitsu
Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya, 4678601, Japan.
World J Surg Oncol. 2014 May 6;12:140. doi: 10.1186/1477-7819-12-140.
Inflammatory pseudotumor (IPT) of the liver is a rare benign lesion. A case of IPT of the liver found in association with a malignant gastrointestinal stromal tumor (GIST) is reported.
A 74-year-old man was admitted to our hospital for a liver tumor. He previously underwent rectal amputation for a malignant GIST. Computed tomography (CT) revealed a low-density area in the liver and dynamic contrast-enhanced MRI (EOB-MRI) showed that the tumor was completely washed out in the delayed phase. 18Fluorine-fluorodeoxyglucose positron emission tomography (FDG-PET) showed strong uptake in the liver. A diagnosis of liver metastasis was made and partial hepatectomy was performed. Microscopic examination showed that the tumor was an IPT.
Differential diagnosis between IPT and malignant neoplasms is difficult. Moreover, FDG-PET revealed strong uptake in the tumor. To our knowledge, this is the first patient reported to have an IPT in association with a rectal GIST. This patient is discussed along with a review of the literature.
肝脏炎性假瘤(IPT)是一种罕见的良性病变。本文报道了一例与恶性胃肠道间质瘤(GIST)相关的肝脏IPT病例。
一名74岁男性因肝脏肿瘤入住我院。他曾因恶性GIST接受直肠切除术。计算机断层扫描(CT)显示肝脏有低密度区,动态对比增强磁共振成像(EOB-MRI)显示肿瘤在延迟期完全廓清。18氟-氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)显示肝脏有强烈摄取。诊断为肝转移并进行了部分肝切除术。显微镜检查显示肿瘤为IPT。
IPT与恶性肿瘤的鉴别诊断困难。此外,FDG-PET显示肿瘤有强烈摄取。据我们所知,这是首例报道的与直肠GIST相关的IPT患者。本文结合文献复习对该患者进行了讨论。