Zhao Jianping, Olino Kelly, Low Leah E, Qiu Suimin, Stevenson Heather L
Department of Pathology, University of Texas Medical Branch, Galveston, TX.
Department of Surgery, University of Texas Medical Branch, Galveston, TX.
ACG Case Rep J. 2019 Feb 13;6(1):e00015. doi: 10.14309/crj.0000000000000015. eCollection 2019 Jan.
Hepatic inflammatory pseudotumors (IPTs) are rare lesions that mimic malignancy clinically, radiologically, and pathologically. The pathophysiology is unknown, and no criteria exist for diagnosis. This series includes 3 cases: 1 patient had recent biliary drainage with bile duct stent placement, and the other 2 patients had hepatic abscess formation before IPT development, which further supports that hepatic IPTs develop in patients with underlying triggers of liver inflammation and injury, including infections and/or bile leakage into the parenchyma. All 3 patients were successfully treated with antibiotics, sparing them surgical intervention. Follow-up showed complete resolution, and none developed recurrences or malignancies.
肝脏炎性假瘤（IPT）是一种罕见病变，在临床、放射学和病理学上都酷似恶性肿瘤。其病理生理学尚不清楚，也没有诊断标准。本系列包括3例：1例患者近期进行了胆管引流并放置了胆管支架，另外2例患者在IPT发生前有肝脓肿形成，这进一步支持肝脏IPT发生于有肝脏炎症和损伤潜在诱因的患者，包括感染和/或胆汁渗入实质。所有3例患者均通过抗生素治疗成功治愈，避免了手术干预。随访显示病变完全消退，无一例复发或发生恶性肿瘤。
