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Anti-HIV drug particles may overcome lymphatic drug insufficiency and associated HIV persistence.

作者信息

Freeling Jennifer P, Ho Rodney J Y

机构信息

Department of Pharmaceutics, University of Washington, Seattle, WA 98195.

Department of Pharmaceutics, University of Washington, Seattle, WA 98195

出版信息

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2512-3. doi: 10.1073/pnas.1406554111. Epub 2014 Jun 2.

DOI:10.1073/pnas.1406554111
PMID:24889644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4078825/
Abstract
摘要

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本文引用的文献

1
Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues.持续性 HIV-1 复制与淋巴组织中抗逆转录病毒药物浓度降低有关。
Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2307-12. doi: 10.1073/pnas.1318249111. Epub 2014 Jan 27.
2
Novel Gd nanoparticles enhance vascular contrast for high-resolution magnetic resonance imaging.新型 Gd 纳米颗粒增强血管对比，实现高分辨率磁共振成像。
PLoS One. 2010 Sep 30;5(9):e13082. doi: 10.1371/journal.pone.0013082.
3
Optimization of lipid-indinavir complexes for localization in lymphoid tissues of HIV-infected macaques.优化脂质-茚地那韦复合物以定位在感染HIV的猕猴的淋巴组织中。
J Acquir Immune Defic Syndr. 2006 Jun;42(2):155-61. doi: 10.1097/01.qai.0000214822.33905.87.
4
Lipid-drug association enhanced HIV-1 protease inhibitor indinavir localization in lymphoid tissues and viral load reduction: a proof of concept study in HIV-2287-infected macaques.脂质-药物结合增强HIV-1蛋白酶抑制剂茚地那韦在淋巴组织中的定位并降低病毒载量：一项在感染HIV-2287的猕猴身上进行的概念验证研究
J Acquir Immune Defic Syndr. 2003 Dec 1;34(4):387-97. doi: 10.1097/00126334-200312010-00005.
5
Afferent pathways of lymph flow within the popliteal node in sheep.绵羊腘淋巴结内淋巴流动的传入途径。
J Anat. 1986 Dec;149:65-75.