Nicolaisen Marianne, Müller Stig, Patel Hitendra R H, Hanssen Tove Aminda
National Continence and Pelvic Floor Center of Norway, University Hospital of North Norway, Tromsø, Norway.
J Clin Nurs. 2014 Dec;23(23-24):3403-14. doi: 10.1111/jocn.12586. Epub 2014 Jun 3.
To assess patients' symptoms, quality of life and satisfaction with information three to four years after radical prostatectomy, radical external beam radiotherapy and postoperative radiotherapy and to analyse differences between treatment groups and the relationship between disease-specific, health-related and overall quality of life and satisfaction with information.
Radical prostate cancer treatments are associated with changes in quality of life. Differences between patients undergoing different treatments in symptoms and quality of life have been reported, but there are limited long-term data comparing radical prostatectomy with radical external beam radiotherapy and postoperative radiotherapy.
A cross-sectional survey design was used.
The study sample included 143 men treated with radical prostatectomy and/or radical external beam radiotherapy. Quality of life was measured using the 12-item Short Form Health Survey and the 50-item Expanded Prostate Cancer Index Composite Instrument. Questions assessing overall Quality of life and satisfaction with information were included. Descriptive statistics and interference statistical methods were applied to analyse the data.
Radical external beam radiotherapy was associated with less urinary incontinence and better urinary function. There were no differences between the groups for disease-specific quality of life sum scores. Sexual quality of life was reported very low in all groups. Disease-specific quality of life and health-related quality of life were associated with overall quality of life. Patients having undergone surgery were more satisfied with information, and there was a positive correlation between quality of life and patient satisfaction.
Pretreatment information and patient education lead to better quality of life and satisfaction. This study indicates a need for structured, pretreatment information and follow-up for all men going through radical prostate cancer treatment.
Long-term quality of life effects should be considered when planning follow-up and information for men after radical prostate cancer treatment. Structured and organised information/education may increase preparedness for symptoms and bother after the treatment, improve symptom management strategies and result in improved quality of life.
评估根治性前列腺切除术、根治性体外照射放疗及术后放疗三到四年后患者的症状、生活质量及对信息的满意度，并分析治疗组之间的差异以及疾病特异性、健康相关和总体生活质量与对信息的满意度之间的关系。
根治性前列腺癌治疗与生活质量的变化相关。已报道不同治疗方式的患者在症状和生活质量方面存在差异，但比较根治性前列腺切除术与根治性体外照射放疗及术后放疗的长期数据有限。
采用横断面调查设计。
研究样本包括143名接受根治性前列腺切除术和/或根治性体外照射放疗的男性。使用12项简短健康调查问卷和50项扩展前列腺癌指数综合工具测量生活质量。纳入评估总体生活质量和对信息满意度的问题。应用描述性统计和干预统计方法分析数据。
根治性体外照射放疗与较少的尿失禁及更好的排尿功能相关。疾病特异性生活质量总分在各组之间无差异。所有组的性生活质量均报告很低。疾病特异性生活质量和健康相关生活质量与总体生活质量相关。接受手术的患者对信息更满意，生活质量与患者满意度之间存在正相关。
术前信息和患者教育可带来更好的生活质量和满意度。本研究表明，对于所有接受根治性前列腺癌治疗的男性，需要进行结构化的术前信息告知和随访。
在为根治性前列腺癌治疗后的男性规划随访和信息告知时，应考虑长期生活质量影响。结构化和有组织的信息/教育可能会增加对治疗后症状和困扰的准备，改善症状管理策略并提高生活质量。
