Su Nan, Lin Jiangtao, Chen Ping, Li Jing, Wu Changgui, Yin Kaisheng, Liu Chuntao, Chen Yiqiang, Zhou Xin, Yuan Yadong, Huang Xingang
Department of Respiratory Diseases, China-Japan Friendship Hospital, Beijing 100029, China.
Department of Respiratory Diseases, China-Japan Friendship Hospital, Beijing 100029, China. Email:
Chin Med J (Engl). 2014;127(11):2030-6.
Little is known about asthma control and perception of asthma among asthmatic patients in China. This study marked the first survey conducted on a national scale that aimed at obtaining baseline information on asthma control and patients' perception of asthma and providing a point of reference for future studies.
This face-to-face, questionnaire-based survey was conducted from April 2007 to March 2008 with 3 069 asthmatic patients from the respiratory outpatient clinics of 36 general hospitals located in 10 geographically dispersed cities.
Consistent with the Global Initiative for Asthma (GINA) guidelines, 28.7% and 45.0% of our patients achieved control and partial control, respectively. Of the patients in the study, only 21.8% had used a peak flow meter (PFM), and 6.6% of these patients used it daily. Inhaled corticosteroids (ICS) plus a long-acting β2 agonist (LABA) and ICS were the two most common medication regimens and were used in 45.6% and 30.4% of patients, respectively. Asthma had a significant effect on the patients' life and work. A considerable number of hospitalizations, emergency department visits, and sick days were observed.
Despite improvements in asthma control and ICS and PFM compliance compared with past literature, the current level of asthma control countrywide continues to fall short of the goals set in the GINA.
在中国,哮喘患者对哮喘控制情况及哮喘认知的了解甚少。本研究是首次在全国范围内开展的调查,旨在获取哮喘控制及患者对哮喘认知的基线信息,并为未来研究提供参考依据。
本研究采用面对面问卷调查的方式,于2007年4月至2008年3月对来自10个地理位置分散城市的36家综合医院呼吸门诊的3069例哮喘患者进行了调查。
根据全球哮喘防治创议(GINA)指南,分别有28.7%和45.0%的患者达到控制和部分控制。在本研究的患者中,仅21.8%使用过峰流速仪(PFM),其中6.6%的患者每日使用。吸入性糖皮质激素(ICS)加长效β2受体激动剂(LABA)和ICS是两种最常用的药物治疗方案,分别有45.6%和30.4%的患者使用。哮喘对患者的生活和工作有显著影响。观察到相当数量的住院、急诊就诊及病假情况。
尽管与既往文献相比,哮喘控制情况以及ICS和PFM的依从性有所改善,但目前全国范围内的哮喘控制水平仍未达到GINA设定的目标。