Su Nan, Lin Jiangtao, Chen Ping, Li Jing, Wu Changgui, Yin Kaisheng, Liu Chuntao, Chen Yiqiang, Zhou Xin, Yuan Yadong, Huang Xingang
Department of Respiratory Diseases, China-Japan Friendship Hospital, Peking University , Beijing , China .
J Asthma. 2013 Oct;50(8):861-70. doi: 10.3109/02770903.2013.808346.
Little is known about asthma control and perception of asthma among asthmatic patients on a national scale in China due to the difficulty of conducting a survey of the large, vastly distributed population of the country. We know that the medical insurance system may not evenly cover all patients and that socioeconomic status varies greatly across cities.
This study marks the first survey conducted on a national scale that was aimed at obtaining baseline information on asthma control and patients' perceptions of asthma and providing a point of reference for future studies.
This face-to-face, questionnaire-based survey was conducted from April 2007 to March 2008 in 3069 asthmatic patients from the respiratory outpatient clinics of 36 general hospitals located in 10 geographically dispersed cities.
Per the Global Initiative for Asthma (GINA) guidelines, 28.7% and 45.0% of our patients achieved complete or partial asthma control, respectively. Of patients in the study, only 21.8% had used a peak flow meter (PFM) and 6.6% of these patients used it daily. Inhaled corticosteroids (ICS) plus a long-acting β2 agonist and ICS were the two most common medication regimens and were used in 45.6% and 30.4% of patients, respectively. Asthma had a significant effect on patients' life and work. A considerable number of hospitalizations, emergency department visits and sick days were also observed.
Despite improvements in asthma control and ICS and PFM compliance compared with past literature, the current level of asthma control countrywide continues to fall short of the goals set in the GINA.
由于在中国对庞大且分布广泛的人口进行调查存在困难，因此在全国范围内，关于哮喘患者的哮喘控制情况以及对哮喘的认知了解甚少。我们知道医疗保险系统可能无法均匀覆盖所有患者，而且不同城市的社会经济状况差异很大。
本研究是首次在全国范围内进行的调查，旨在获取哮喘控制及患者对哮喘认知的认知的基线信息，并为未来研究提供参考依据。
这项基于问卷的面对面调查于2007年4月至2008年3月在来自10个地理位置分散的城市的36家综合医院呼吸门诊的3069例哮喘患者中进行。
根据全球哮喘防治创议（GINA）指南，我们的患者中分别有28.7%和45.0%实现了完全或部分哮喘控制。在研究患者中，仅21.8%使用过峰流速仪（PFM），其中6.6%的患者每天使用。吸入性糖皮质激素（ICS）加长效β2受体激动剂和ICS是两种最常用的药物治疗方案，分别有45.6%和30.4%的患者使用。哮喘对患者的生活和工作有显著影响。还观察到相当数量的住院、急诊就诊和病假情况。
尽管与以往文献相比，哮喘控制以及ICS和PFM的依从性有所改善，但目前全国范围内的哮喘控制水平仍未达到GINA设定的目标。
