IncI1序列型2质粒pJIE512b的全序列测定表明blaCMY - 2是从一个IncA/C质粒转移而来的。
Complete sequencing of IncI1 sequence type 2 plasmid pJIE512b indicates mobilization of blaCMY-2 from an IncA/C plasmid.
作者信息
Tagg Kaitlin A, Iredell Jonathan R, Partridge Sally R
机构信息
Centre for Infectious Diseases and Microbiology, Westmead Millennium Institute, and The University of Sydney, Westmead, New South Wales, Australia.
Centre for Infectious Diseases and Microbiology, Westmead Millennium Institute, and The University of Sydney, Westmead, New South Wales, Australia
出版信息
Antimicrob Agents Chemother. 2014 Aug;58(8):4949-52. doi: 10.1128/AAC.02773-14. Epub 2014 Jun 2.
Abstract
Sequencing of pJIE512b, a 92.3-kb IncI1 sequence type 2 (ST2) plasmid carrying bla(CMY-2), revealed a bla(CMY-2) context that appeared to have been mobilized from an IncA/C plasmid by the insertion sequence IS1294. A comparison with published plasmids suggests that bla(CMY-2) has been mobilized from IncA/C to IncI1 plasmids more than once by IS1294-like elements. Alignment of pJIE512b with the only other available IncI1 ST2 plasmid revealed differences across the backbones, indicating variability within this sequence type.
摘要
对携带bla(CMY - 2)的92.3 kb IncI1序列类型2（ST2）质粒pJIE512b进行测序，结果显示bla(CMY - 2)的上下游序列似乎是通过插入序列IS1294从IncA/C质粒中转移过来的。与已发表质粒的比较表明，bla(CMY - 2)已不止一次通过类似IS1294的元件从IncA/C质粒转移到IncI1质粒中。将pJIE512b与唯一另一个可用的IncI1 ST2质粒进行比对，结果显示主干序列存在差异，表明该序列类型存在变异性。
相似文献
1
Complete sequencing of IncI1 sequence type 2 plasmid pJIE512b indicates mobilization of blaCMY-2 from an IncA/C plasmid.IncI1序列型2质粒pJIE512b的全序列测定表明blaCMY - 2是从一个IncA/C质粒转移而来的。
Antimicrob Agents Chemother. 2014 Aug;58(8):4949-52. doi: 10.1128/AAC.02773-14. Epub 2014 Jun 2.
2
High Heterogeneity of Escherichia coli Sequence Types Harbouring ESBL/AmpC Genes on IncI1 Plasmids in the Colombian Poultry Chain.哥伦比亚家禽产业链中携带ESBL/AmpC基因的IncI1质粒上大肠杆菌序列类型的高度异质性
PLoS One. 2017 Jan 26;12(1):e0170777. doi: 10.1371/journal.pone.0170777. eCollection 2017.
3
IncI1 plasmids carrying bla(CTX-M-1) or bla(CMY-2) genes in Escherichia coli from healthy humans and animals in Tunisia.来自突尼斯健康人和动物的大肠杆菌中携带bla(CTX-M-1)或bla(CMY-2)基因的IncI1质粒。
Microb Drug Resist. 2014 Oct;20(5):495-500. doi: 10.1089/mdr.2013.0224. Epub 2014 May 14.
4
Host-Specific Patterns of Genetic Diversity among IncI1-Iγ and IncK Plasmids Encoding CMY-2 β-Lactamase in Escherichia coli Isolates from Humans, Poultry Meat, Poultry, and Dogs in Denmark.丹麦人、禽肉、家禽和狗源大肠杆菌中编码CMY-2β-内酰胺酶的IncI1-Iγ和IncK质粒的宿主特异性遗传多样性模式
Appl Environ Microbiol. 2016 Jul 15;82(15):4705-14. doi: 10.1128/AEM.00495-16. Print 2016 Aug 1.
5
Novel genetic environment of the plasmid-mediated KPC-3 gene detected in Escherichia coli and Citrobacter freundii isolates from China.中国产大肠埃希菌和弗氏柠檬酸杆菌中介导 KPC-3 基因的质粒新型遗传环境。
Eur J Clin Microbiol Infect Dis. 2011 Apr;30(4):575-80. doi: 10.1007/s10096-010-1124-7. Epub 2010 Dec 14.
6
Expansive spread of IncI1 plasmids carrying blaCMY-2 amongst Escherichia coli.携带 blaCMY-2 的 IncI1 质粒在大肠杆菌中的广泛传播。
Int J Antimicrob Agents. 2014 Sep;44(3):203-8. doi: 10.1016/j.ijantimicag.2014.04.016. Epub 2014 Jun 6.
7
Point mutations in the inc antisense RNA gene are associated with increased plasmid copy number, expression of blaCMY-2 and resistance to piperacillin/tazobactam in Escherichia coli.反义 RNA 基因 inc 点突变与质粒拷贝数增加、blaCMY-2 表达和大肠埃希菌对哌拉西林/他唑巴坦的耐药性有关。
J Antimicrob Chemother. 2012 Feb;67(2):339-45. doi: 10.1093/jac/dkr479. Epub 2011 Nov 24.
8
Occurrence of bla on an IncI1 plasmid in multidrug-resistant Escherichia coli from a tertiary referral hospital in India.bla 基因在印度一家三级转诊医院耐多药大肠杆菌中的 IncI1 质粒上的出现。
J Glob Antimicrob Resist. 2018 Sep;14:78-82. doi: 10.1016/j.jgar.2018.02.021. Epub 2018 Mar 2.
9
Emergence of a multiresistant KPC-3 and VIM-1 carbapenemase-producing Escherichia coli strain in Spain.西班牙出现一株产多耐药KPC-3和VIM-1碳青霉烯酶的大肠杆菌菌株。
J Antimicrob Chemother. 2014 Jul;69(7):1792-5. doi: 10.1093/jac/dku055. Epub 2014 Feb 28.
10
Sporadic occurrence of CMY-2-producing multidrug-resistant Escherichia coli of ST-complexes 38 and 448, and ST131 in Norway.挪威出现散发的产 CMY-2 的多重耐药型大肠埃希菌，其 ST 复合群为 38 和 448 以及 ST131。
Clin Microbiol Infect. 2010 Feb;16(2):171-8. doi: 10.1111/j.1469-0691.2009.02861.x. Epub 2009 Jun 22.
引用本文的文献
1
Stool carriage of CTX-M/CMY-producing in a Chinese tertiary hospital in Shenzhen, China.中国深圳一家三级医院中产CTX-M/CMY的粪便携带情况。
Front Cell Infect Microbiol. 2025 Mar 13;15:1544757. doi: 10.3389/fcimb.2025.1544757. eCollection 2025.
2
A Novel CMY Variant Confers Transferable High-Level Resistance to Ceftazidime-Avibactam in Multidrug-Resistant Escherichia coli.一种新型CMY变体赋予多重耐药性大肠杆菌对头孢他啶-阿维巴坦的可转移高水平耐药性。
Microbiol Spectr. 2023 Feb 14;11(2):e0334922. doi: 10.1128/spectrum.03349-22.
3
Emergence of a Rissen ST469 clinical isolate carrying in China.中国出现一株携带 的 Rissen ST469 临床分离株。
Front Cell Infect Microbiol. 2022 Aug 8;12:936649. doi: 10.3389/fcimb.2022.936649. eCollection 2022.
4
Spread and Molecular Characteristics of Carrying -Like Genes from Farms in China.中国养殖场携带样基因的传播和分子特征。
Microbiol Spectr. 2022 Aug 31;10(4):e0054522. doi: 10.1128/spectrum.00545-22. Epub 2022 Jul 19.
5
Occurrence and molecular epidemiology of fosA3-bearing Escherichia coli from ducks in Shandong province of China.中国山东省鸭源产 ESBLs 大肠杆菌中 fosA3 的携带情况及分子流行病学研究。
Poult Sci. 2022 Mar;101(3):101620. doi: 10.1016/j.psj.2021.101620. Epub 2021 Nov 30.
6
Genomic diversity of antimicrobial resistance in non-typhoidal in Victoria, Australia.澳大利亚维多利亚州非伤寒沙门氏菌的抗菌药物耐药性的基因组多样性。
Microb Genom. 2021 Dec;7(12). doi: 10.1099/mgen.0.000725.
7
Incompatibility Group I1 (IncI1) Plasmids: Their Genetics, Biology, and Public Health Relevance.I 类不相容群 1（IncI1）质粒：其遗传学、生物学和公共卫生相关性。
Microbiol Mol Biol Rev. 2021 Apr 28;85(2). doi: 10.1128/MMBR.00031-20. Print 2021 May 19.
8
Whole-genome analyses of extended-spectrum or AmpC β-lactamase-producing Escherichia coli isolates from companion dogs in Japan.对来自日本伴侣犬的产超广谱或 AmpC β-内酰胺酶的大肠杆菌分离株的全基因组分析。
PLoS One. 2021 Feb 5;16(2):e0246482. doi: 10.1371/journal.pone.0246482. eCollection 2021.
9
Escherichia coli Sequence Type 457 Is an Emerging Extended-Spectrum-β-Lactam-Resistant Lineage with Reservoirs in Wildlife and Food-Producing Animals.大肠杆菌序列型 457 是一种新兴的具有野生动物和食用动物储存库的扩展谱β-内酰胺耐药谱系。
Antimicrob Agents Chemother. 2020 Dec 16;65(1). doi: 10.1128/AAC.01118-20.
10
Plasmid profiling and incompatibility grouping of multidrug resistant Salmonella enterica serovar Typhi isolates in Nairobi, Kenya.肯尼亚内罗毕多重耐药伤寒沙门氏菌分离株的质粒谱分析与不相容性分组
BMC Res Notes. 2019 Jul 16;12(1):422. doi: 10.1186/s13104-019-4468-9.
本文引用的文献
1
High diversity of plasmids harbouring blaCMY-2 among clinical Escherichia coli isolates from humans and companion animals in the upper Midwestern USA.美国中西部上地区人类和伴侣动物临床分离大肠杆菌中携带 blaCMY-2 的质粒多样性高。
J Antimicrob Chemother. 2014 Jun;69(6):1492-6. doi: 10.1093/jac/dku011. Epub 2014 Feb 4.
2
Characterization of blaCMY plasmids and their possible role in source attribution of Salmonella enterica serotype Typhimurium infections.blaCMY质粒的特征及其在鼠伤寒沙门氏菌感染源追踪中可能发挥的作用。
Foodborne Pathog Dis. 2014 Apr;11(4):301-6. doi: 10.1089/fpd.2013.1670. Epub 2014 Jan 31.
3
Complete nucleotide sequence of a conjugative IncF plasmid from an Escherichia coli isolate of equine origin containing blaCMY-2 within a novel genetic context.马源大肠杆菌分离株中含有 blaCMY-2 的可接合 IncF 质粒的完整核苷酸序列，其位于新的遗传环境中。
FEMS Microbiol Lett. 2014 Mar;352(1):123-7. doi: 10.1111/1574-6968.12364. Epub 2014 Jan 6.
4
Conjugative transfer of an IncA/C plasmid-borne blaCMY-2 gene through genetic re-arrangements with an IncX1 plasmid.通过与 IncX1 质粒的遗传重排，传递 IncA/C 质粒携带的 blaCMY-2 基因。
BMC Microbiol. 2013 Nov 21;13:264. doi: 10.1186/1471-2180-13-264.
5
Diversity of plasmid replicons encoding the bla(CMY-2) gene in broad-spectrum cephalosporin-resistant Escherichia coli from livestock animals in Japan.日本家畜动物中广谱头孢菌素耐药大肠杆菌携带 bla(CMY-2) 基因的质粒复制子多样性。
Foodborne Pathog Dis. 2013 Mar;10(3):243-9. doi: 10.1089/fpd.2012.1306.
6
Emergence of extended-spectrum β-lactam resistance among Escherichia coli at a US academic children's hospital is clonal at the sequence type level for CTX-M-15, but not for CMY-2.美国一家学术型儿童医院的大肠埃希菌中出现了超广谱β-内酰胺耐药，CTX-M-15 的序列型水平存在克隆传播，但 CMY-2 不存在。
Int J Antimicrob Agents. 2013 May;41(5):414-20. doi: 10.1016/j.ijantimicag.2013.01.006. Epub 2013 Feb 20.
7
DNA sequence analysis of plasmids from multidrug resistant Salmonella enterica serotype Heidelberg isolates.对多重耐药性肠炎沙门氏菌海德堡血清型分离株质粒的 DNA 序列分析。
PLoS One. 2012;7(12):e51160. doi: 10.1371/journal.pone.0051160. Epub 2012 Dec 10.
8
Plasmid typing and genetic context of AmpC β-lactamases in Enterobacteriaceae lacking inducible chromosomal ampC genes: findings from a Spanish hospital 1999-2007.1999-2007 年西班牙某医院缺乏可诱导染色体 ampC 基因的肠杆菌科细菌中 AmpC β-内酰胺酶的质粒分型和遗传结构
J Antimicrob Chemother. 2012 Jan;67(1):115-22. doi: 10.1093/jac/dkr412. Epub 2011 Oct 6.
9
Comparative genomics and phylogeny of the IncI1 plasmids: a common plasmid type among porcine enterotoxigenic Escherichia coli.比较 IncI1 质粒的基因组学和系统发生：猪肠产毒性大肠杆菌中的一种常见质粒类型。
Plasmid. 2011 Sep;66(3):144-51. doi: 10.1016/j.plasmid.2011.07.003. Epub 2011 Aug 6.
10
Analysis of antibiotic resistance regions in Gram-negative bacteria.革兰氏阴性菌耐药区域分析。
FEMS Microbiol Rev. 2011 Sep;35(5):820-55. doi: 10.1111/j.1574-6976.2011.00277.x. Epub 2011 Jun 16.
Zotero 插件